Endometrial cancer is the most common gynecological cancers in developed countries.
Many of the mechanisms involved in its initiation and progression remain unclear. Analysis …

High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and
the majority of cases present with metastasis and late-stage disease. Over the last few …

Long non-coding RNAs (lncRNAs) refer to elements of genomic transcription with more than
200 nucleotides that are not translated into proteins, but have crucial roles in cancer …

High-grade serous cancer (HGSC) is the most common subtype of ovarian cancer. HGSC is
highly aggressive with poor patient outcomes, and a deeper understanding of HGSC …

Cancer-associated mesothelial cells (CAMCs) in the tumor microenvironment are thought to
promote growth and immune evasion. We find that, in mouse and human ovarian tumors …

Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide,
mainly because of its initially asymptomatic nature and consequently late diagnosis. Long …

The tight junction protein claudin 6 (CLDN6) is differentially expressed on cancer cells with
almost no expression in healthy tissue. However, achieving therapeutic MAb specificity for …

Even after debulking surgery combined with chemotherapy or new adjuvant chemotherapy
paired with internal surgery, the average year of disease free survival in advanced ovarian …

High-grade serous ovarian carcinoma (HGSOC) represents the most common form of
epithelial ovarian carcinoma. The absence of specific symptoms leads to late-stage …

Genetic heterogeneity in ovarian cancer indicates the need for personalised treatment
approaches. Currently, very few G-protein coupled receptors (GPCRs) have been …