Machine learning in enzyme engineering
Enzyme engineering plays a central role in developing efficient biocatalysts for
biotechnology, biomedicine, and life sciences. Apart from classical rational design and …
biotechnology, biomedicine, and life sciences. Apart from classical rational design and …
PANNZER2: a rapid functional annotation web server
The unprecedented growth of high-throughput sequencing has led to an ever-widening
annotation gap in protein databases. While computational prediction methods are available …
annotation gap in protein databases. While computational prediction methods are available …
[HTML][HTML] Biochemical functional predictions for protein structures of unknown or uncertain function
CL Mills, PJ Beuning, MJ Ondrechen - Computational and structural …, 2015 - Elsevier
With the exponential growth in the determination of protein sequences and structures via
genome sequencing and structural genomics efforts, there is a growing need for reliable …
genome sequencing and structural genomics efforts, there is a growing need for reliable …
Annotated genes and nonannotated genomes: cross‐species use of Gene Ontology in ecology and evolution research
Recent advances in molecular technologies have opened up unprecedented opportunities
for molecular ecologists to better understand the molecular basis of traits of ecological and …
for molecular ecologists to better understand the molecular basis of traits of ecological and …
[HTML][HTML] A large-scale evaluation of computational protein function prediction
Automated annotation of protein function is challenging. As the number of sequenced
genomes rapidly grows, the overwhelming majority of protein products can only be …
genomes rapidly grows, the overwhelming majority of protein products can only be …
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Background A major bottleneck in our understanding of the molecular underpinnings of life
is the assignment of function to proteins. While molecular experiments provide the most …
is the assignment of function to proteins. While molecular experiments provide the most …
Strong phenotypic plasticity limits potential for evolutionary responses to climate change
V Oostra, M Saastamoinen, BJ Zwaan… - Nature …, 2018 - nature.com
Phenotypic plasticity, the expression of multiple phenotypes from one genome, is a
widespread adaptation to short-term environmental fluctuations, but whether it facilitates …
widespread adaptation to short-term environmental fluctuations, but whether it facilitates …
Sargasso Sea Vibrio bacteria: Underexplored potential pathovars in a perturbed habitat
We fully sequenced the genomes of 16 Vibrio cultivars isolated from eel larvae, plastic
marine debris (PMD), the pelagic brown macroalga Sargassum, and seawater samples …
marine debris (PMD), the pelagic brown macroalga Sargassum, and seawater samples …
Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution
The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that
transmits a number of human viral diseases, including dengue and Chikungunya fevers …
transmits a number of human viral diseases, including dengue and Chikungunya fevers …
[HTML][HTML] Optimizing cellulase production from Aspergillus flavus using response surface methodology and machine learning models
The study aims to optimize cellulase (CMCase) production by Aspergillus flavus using wheat
straw, an abundantly available lignocellulosic waste, as a substrate. Three parameters, ie …
straw, an abundantly available lignocellulosic waste, as a substrate. Three parameters, ie …