A systematic review and random-effects model network meta-analysis were conducted to
compare the efficacy, acceptability, tolerability, and safety of antidepressants to treat adults …

Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

A significant clinical issue encountered after a successful acute major depressive disorder
(MDD) treatment is the relapse of depressive symptoms. Although continuing maintenance …

The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

A revision of the 2000 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken to …

" It is a delight to see the Fourth Edition of Sommers-Flanagans's excellent work. They
understand counseling and therapy, their writing is clear, and this book will be enjoyed by …

Objective: Treatment resistance is a common clinical phenomenon in depression. However,
current unitary models of staging fail to represent its complexity. We aimed to devise a model …

Recent technological advances offer an opportunity to further elucidate the complex cytokine
network in Major Depressive Disorder (MDD). Twenty cytokines were simultaneously …