Nanoparticles are rapidly being developed and trialed to overcome several limitations of
traditional drug delivery systems and are coming up as a distinct therapeutics for cancer …

A causal role was recently attributed to inflammation in many malignant diseases, including
breast cancer. The different inflammatory mediators that are involved in this disease include …

The safe and efficient delivery of chemotherapeutic agents remains critical to anticancer
therapy. Herein, we report on a targeted drug delivery system based upon a modified cell …

Successful combinations of radiotherapy and immunotherapy depend on the presence of
live T cells within the tumor; however, radiotherapy is believed to damage T cells. Here …

Endothelial cells lining blood vessels are exposed to various hemodynamic forces
associated with blood flow. These include fluid shear, the tangential force derived from the …

A key step in angiogenesis is the upregulation of growth factor receptors on endothelial
cells. Here, we demonstrate that a small regulatory microRNA, miR-296, has a major role in …

Glioma is a fatal disease with limited treatment options and very short survival. Although
chemotherapy is one of the most important strategies in glioma treatment, it remains …

Nu61, a radiation-resistant human tumor xenograft, was selected from a parental
radiosensitive tumor SCC-61 by eight serial cycles of passage in athymic nude mice and in …

Angiogenesis, the outgrowth of blood vessels, is crucial in development, disease and
regeneration. Studying angiogenesis in vitro remains challenging because the capillary …

purpose. To evaluate the association of serum factors with the severity of diabetic
retinopathy and to assess their presence in retinal tissue obtained at autopsy. methods. The …