[HTML][HTML] A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

[HTML][HTML] Multiorgan-on-a-chip: a systemic approach to model and decipher inter-organ communication

N Picollet-D'hahan, A Zuchowska, I Lemeunier… - Trends in …, 2021 - cell.com
Multiorgan-on-a-chip (multi-OoC) platforms have great potential to redefine the way in which
human health research is conducted. After briefly reviewing the need for comprehensive …

In-line analysis of organ-on-chip systems with sensors: Integration, fabrication, challenges, and potential

S Fuchs, S Johansson, AØ Tjell, G Werr… - ACS Biomaterials …, 2021 - ACS Publications
Organ-on-chip systems are promising new in vitro research tools in medical,
pharmaceutical, and biological research. Their main benefit, compared to standard cell …

Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease

L Amirifar, A Shamloo, R Nasiri, NR de Barros… - Biomaterials, 2022 - Elsevier
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …

[HTML][HTML] Breakthroughs and applications of organ-on-a-chip technology

MC Koyilot, P Natarajan, CR Hunt, S Sivarajkumar… - Cells, 2022 - mdpi.com
Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in
vitro cell culture that has a promising future in the healthcare industry. The numerous …

Gut-on-a-chip: Current progress and future opportunities

N Ashammakhi, R Nasiri, NR De Barros, P Tebon… - Biomaterials, 2020 - Elsevier
Organ-on-a-chip technology tries to mimic the complexity of native tissues in vitro. Important
progress has recently been made in using this technology to study the gut with and without …

[HTML][HTML] 3D printing techniques and their applications to organ-on-a-chip platforms: a systematic review

V Carvalho, I Gonçalves, T Lage, RO Rodrigues… - Sensors, 2021 - mdpi.com
Three-dimensional (3D) in vitro models, such as organ-on-a-chip platforms, are an emerging
and effective technology that allows the replication of the function of tissues and organs …

Organ‐on‐a‐chip: A preclinical microfluidic platform for the progress of nanomedicine

RO Rodrigues, PC Sousa, J Gaspar, M Bañobre‐López… - Small, 2020 - Wiley Online Library
Despite the progress achieved in nanomedicine during the last decade, the translation of
new nanotechnology‐based therapeutic systems into clinical applications has been slow …

[HTML][HTML] Skin-on-a-chip models: General overview and future perspectives

I Risueño, L Valencia, JL Jorcano, D Velasco - APL bioengineering, 2021 - pubs.aip.org
Over the last few years, several advances have been made toward the development and
production of in vitro human skin models for the analysis and testing of cosmetic and …

[HTML][HTML] Organ-on-a-chip platforms for accelerating the evaluation of nanomedicine

X Chen, YS Zhang, X Zhang, C Liu - Bioactive Materials, 2021 - Elsevier
Nanomedicine involves the use of engineered nanoscale materials in an extensive range of
diagnostic and therapeutic applications and can be applied to the treatment of many …