A comprehensive review of bioactive peptides obtained from animal byproducts and their applications

J Bechaux, P Gatellier, JF Le Page, Y Drillet… - Food & function, 2019 - pubs.rsc.org
Livestock generates high quantities of residues, which has become a major socioeconomic
issue for the meat industry. This review focuses on the identification of bioactive peptides …

In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia

SA Alsagaby, D Iqbal, I Ahmad, H Patel, SA Mir… - Scientific reports, 2022 - nature.com
Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study,
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …

Nutraceutical potential of selected wild edible fruits of the Indian Himalayan region

ID Bhatt, S Rawat, A Badhani, RS Rawal - Food chemistry, 2017 - Elsevier
Wild edible fruits contribute significantly to the nutritional security of mankind across the
globe. However, detailed analyses of health promoting bioactive compounds and …

Targeting integrated stress response with ISRIB combined with imatinib treatment attenuates RAS/RAF/MAPK and STAT5 signaling and eradicates chronic myeloid …

W Dudka, G Hoser, SS Mondal, L Turos-Korgul… - BMC cancer, 2022 - Springer
The integrated stress response (ISR) facilitates cellular adaptation to unfavorable conditions
by reprogramming the cellular response. ISR activation was reported in neurological …

Molecular rationale delineating the role of lycopene as a potent HMG-CoA reductase inhibitor: in vitro and in silico study

SS Alvi, D Iqbal, S Ahmad, MS Khan - Natural product research, 2016 - Taylor & Francis
This study initially aimed to depict the molecular rationale evolving the role of lycopene in
inhibiting the enzymatic activity of β-hydroxy-β-methylglutaryl-CoA (HMG-CoA) reductase via …

Exploring the binding pattern of geraniol with acetylcholinesterase through in silico docking, molecular dynamics simulation, and in vitro enzyme inhibition kinetics …

D Iqbal, MS Khan, M Waiz, MT Rehman, M Alaidarous… - Cells, 2021 - mdpi.com
Acetylcholinesterase (AChE) inhibition is a key element in enhancing cholinergic
transmission and subsequently relieving major symptoms of several neurological and …

Hydroethanolic Extract of Prunus domestica L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic Diseases

H Ullah, E Sommella, C Santarcangelo, D D'Avino… - Nutrients, 2022 - mdpi.com
High consumption of fruit and vegetables has an inverse association with cardiometabolic
risk factors. This study aimed to chemically characterize the hydroethanolic extract of P …

[PDF][PDF] Bin Dukhyil

D Iqbal, MT Rehman - 2022 - academia.edu
Neurodegenerative disorders involve various pathophysiological pathways, and finding a
solution for these issues is still an uphill task for the scientific community. In the present …

Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait

D Iqbal, MS Khan, MS Khan, S Ahmad… - Lipids in health and …, 2015 - Springer
Background The current perspective for the search of 3-hydroxy-3-methyl-glutaryl-coenzyme
A (HMG-CoA) reductase inhibitor has been shifted towards a natural agent also having …

Soyasapogenol-B as a potential multitarget therapeutic agent for neurodegenerative disorders: molecular docking and dynamics study

D Iqbal, SMD Rizvi, MT Rehman, MS Khan… - Entropy, 2022 - mdpi.com
Neurodegenerative disorders involve various pathophysiological pathways, and finding a
solution for these issues is still an uphill task for the scientific community. In the present …