G-quadruplex DNA for construction of biosensors

H Yang, Y Zhou, J Liu - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
DNA-based biosensors have been widely used for its stable chemical properties, cost-
effectiveness, and easy modification. G-quadruplex (G4) DNA has attracted growing interest …

[PDF][PDF] Recent developments in G-quadruplex probes

DL Ma, Z Zhang, M Wang, L Lu, HJ Zhong… - Chemistry & Biology, 2015 - cell.com
Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast …

W Long, BX Zheng, Y Li, XH Huang, DM Lin… - Nucleic acids …, 2022 - academic.oup.com
DNA G4-structures from human c-MYC promoter and telomere are considered as important
drug targets; however, the developing of small-molecule-based fluorescent binding ligands …

Design of Modular G‐quadruplex Ligands

AR Duarte, E Cadoni, AS Ressurreição… - …, 2018 - Wiley Online Library
Guanine‐rich nucleic acid sequences able to form four‐stranded structures (G‐
quadruplexes, G4) play key cellular regulatory roles and are considered as promising drug …

Green and red fluorescent dyes for translational applications in imaging and sensing analytes: A dual‐color flag

E Oliveira, E Bértolo, C Núñez, V Pilla… - …, 2018 - Wiley Online Library
Red and green are two of the most‐preferred colors from the entire chromatic spectrum, and
red and green dyes are widely used in biochemistry, immunohistochemistry, immune …

Dimeric G-quadruplex: an effective nucleic acid scaffold for lighting up thioflavin T

S Jing, Q Liu, Y Jin, B Li - Analytical Chemistry, 2020 - ACS Publications
As a recently identified higher-order quadruplex (G4) structure, the G4 dimer possesses
unique structure and biological functions. In this work, we found accidentally that two tandem …

A twice-as-smart synthetic G-quartet: PyroTASQ is both a smart quadruplex ligand and a smart fluorescent probe

A Laguerre, L Stefan, M Larrouy, D Genest… - Journal of the …, 2014 - ACS Publications
Recent and unambiguous evidences of the formation of DNA and RNA G-quadruplexes in
cells has provided solid support for these structures to be considered as valuable targets in …

Guidelines for G-quadruplexes: I. in vitro characterization

Y Luo, A Granzhan, J Marquevielle, A Cucchiarini… - Biochimie, 2023 - Elsevier
Besides the well-known DNA double-helix, non-canonical nucleic acid structures regulate
crucial biological activities. Among these oddities, guanine-rich DNA sequences can form …

Dicyanomethylene-functionalized squaraine as a highly selective probe for parallel G-quadruplexes

B Jin, X Zhang, W Zheng, X Liu, J Zhou… - Analytical …, 2014 - ACS Publications
DNA sequences that can form G-quadruplexes (G4s) are highly prevalent in the genome.
However, the structures and functions of most G4-forming sequences in the genome are …

An effective fluorescent optical sensor: Thiazolo-thiazole based dye exhibiting anion/cation sensitivities and acidochromism

Z Dikmen, O Turhan, M Yaman, V Bütün - Journal of Photochemistry and …, 2021 - Elsevier
Abstract Fluorescent 2, 5-bis (4-hydroxyphenyl) thiazolo [5, 4-d] thiazole (HPhTT) sensor
molecule consisting of thiazolo-thiazole (TTz) binding central unit and phenolic signalling …