Abstract Positron Emission Tomography (PET) experienced accelerated development and
has become an established method for medical research and clinical routine diagnostics on …

Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …

Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone)
ligands - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC12123E Royal …

In recent years, Positron Emission Tomography (PET) has become a practical, high
performance clinical imaging modality for visualization of biological process within the living …

Hydroxypyridinones (HPs) are a family of N-heterocyclic core chelators which, based on
their specific metal-coordination, easy manipulation/derivatization and biocompatibility, have …

Due to its long half-life (78 h) and decay properties (77% electron capture, 23% β+, Emax=
897 keV, Eav= 397 keV, Eγ= 909 keV, Iγ= 100%) 89Zr is an appealing radionuclide for …

Curcumin (CUR) and curcuminoids complexes labeled with fluorine-18 or technetium-99m
have recently shown their potential as diagnostic tools for Alzheimer's disease. Gallium-68 is …

Derivatives of 3, 4-hydroxypyridinones have been extensively studied for in vivo Fe3+
sequestration. Deferiprone, a 1, 2-dimethyl-3, 4-hydroxypyridinone, is now routinely used for …

Hydroxypyridinones (HPs) are a family of N-heterocyclic metal chelators, which have been
an attractive target in the development of a variety of new pharmaceutical drugs, due to their …