Management of patients at risk for and with left ventricular thrombus: a scientific statement from the American Heart Association

GN Levine, JW McEvoy, JC Fang, C Ibeh… - Circulation, 2022 - Am Heart Assoc
Despite the many advances in cardiovascular medicine, decisions concerning the
diagnosis, prevention, and treatment of left ventricular (LV) thrombus often remain …

Systematic review of efficacy of direct oral anticoagulants and vitamin K antagonists in left ventricular thrombus

L Huang, Y Tan, Y Pan - ESC Heart Failure, 2022 - Wiley Online Library
Aims Left ventricular thrombus (LVT) increases the risk of thrombotic events and mortality.
Vitamin K antagonists (VKAs) used to treat LVT have several known risks, as a result of …

Trial sequential analysis of efficacy and safety of direct oral anticoagulants and vitamin K antagonists against left ventricular thrombus

T Kitano, Y Nabeshima, M Kataoka, M Takeuchi - Scientific Reports, 2023 - nature.com
Meta-analysis may increase the risk of random errors. Trial sequential analysis (TSA) has
been developed to adjust for these random errors. We conducted TSA on the efficacy and …

When Direct Oral Anticoagulants Should Not Be Standard Treatment: JACC State-of-the-Art Review

A Bejjani, CD Khairani, A Assi, G Piazza… - Journal of the American …, 2024 - jacc.org
For most patients, direct oral anticoagulants (DOACs) are preferred over vitamin K
antagonists for stroke prevention in atrial fibrillation and for venous thromboembolism …

An updated review of the efficacy and safety of direct oral anticoagulants in treatment of left ventricular thrombus

KA Honan, A Jogimahanti, T Khair - The American Journal of Medicine, 2022 - Elsevier
Left ventricular (LV) thrombus is a potentially serious complication affecting males and
females with ischemic and nonischemic cardiomyopathy—specifically, after acute …

Direct oral anticoagulants: navigating through clinical challenges

M Ioannou, E Leonidou, I Chaziri… - Cardiovascular Drugs and …, 2024 - Springer
Abstract Purpose Direct oral anticoagulants (DOACs) have been approved, for over a
decade, by both European and American medicine agencies, for treatment and prevention …

Direct oral anticoagulants (DOAC) versus vitamin K antagonist in left ventricular thrombus: An updated meta‐analysis

DB Shrestha, S Dawadi, B Dhakal… - Health Science …, 2023 - Wiley Online Library
Abstract Background and Aims Current clinical guidelines for treating left ventricular
thrombus (LVT) are limited by inadequate evidence to inform the comparative efficacy of oral …

[HTML][HTML] Apixaban in patients with post-myocardial infarction left ventricular thrombus: a randomized clinical trial

AA Youssef, MA Alrefae, HH Khalil, HI Abdullah… - CJC open, 2023 - Elsevier
Background Direct oral anticoagulants are frequently used to treat post-myocardial infarction
(MI) left ventricular thrombus (LVT). This study was conducted to evaluate the efficacy and …

Direct oral anticoagulation versus warfarin in left ventricular thrombus: pooled analysis of randomized controlled trials

AO Sahlén, H Jiang, YH Lau, L Cuenza… - The Journal of …, 2023 - Wiley Online Library
Patients with impaired left ventricular (LV) function can develop LV thrombus, a potentially
life‐threatening condition due to risk of stroke and embolization. Conventional treatment with …

[HTML][HTML] Are direct oral anticoagulants preferable to warfarin for the treatment of left ventricular thrombi? A Bayesian meta-analysis of randomized controlled trials

A Sayed, M Ghonim, M Ghonim, AK Awad… - American Heart Journal …, 2021 - Elsevier
Background There is no clear consensus on the optimal choice of anticoagulant in patients
with left ventricular thrombi (LVT). Given the potentially fatal complications associated with …