Patterns of transcriptional activity are encoded in our genome through regulatory elements
such as promoters or enhancers that, paradoxically, contain similar assortments of …

Since the advent of sequencing techniques and due to their continuous evolution, it has
become easier and less expensive to obtain the complete genome sequence of any …

Highlights•Synthetic biology applications rely on collections of sequence-verified DNA
parts.•The choice of DNA parts in a construct determines its utility and effectiveness.• …

Androgen insensitivity syndrome (AIS) is a difference of sex development (DSD)
characterized by different degrees of undervirilization in individuals with a 46, XY karyotype …

Medicago truncatula, model legume and alfalfa relative, has served as an essential resource
for advancing our understanding of legume physiology, functional genetics, and crop …

Abstract Background 5'untranslated regions (5'UTRs) are essential modulators of protein
translation. Predicting the impact of 5'UTR variants is challenging and rarely performed in …

Chinese Tan sheep lambs are recognised for having tight 'spring-like'curly wool when
young, but this phenotype disappears with age. This wool consists of shorter, fine wool fibres …

Many organisms, including cosmopolitan drosophilids, show circadian plasticity, varying
their activity with changing dawn–dusk intervals. How this behaviour evolves is unclear …

Lysine lactylation (Kla) is a kind of novel post-translational modification (PTM) that
participates in gene expression and various metabolic processes. Nannochloropsis has a …

Alternative splicing (AS) is a key element of eukaryotic gene expression that increases
transcript and proteome diversity in cells, thereby altering their responses to external stimuli …