Genetic determination of the hypothalamic-pituitary-thyroid axis: where do we stand?

M Medici, WE Visser, TJ Visser, RP Peeters - Endocrine reviews, 2015 - academic.oup.com
For a long time it has been known that both hypo-and hyperthyroidism are associated with
an increased risk of morbidity and mortality. In recent years, it has also become clear that …

Maternal genotype and severe preeclampsia: a HuGE review

FM Fong, MK Sahemey, G Hamedi… - American journal of …, 2014 - academic.oup.com
Severe preeclampsia is a common cause of maternal and perinatal morbidity worldwide.
The disease clusters in families; however, individual genetic studies have produced …

Association of thyroid function test abnormalities with preeclampsia: a systematic review and meta-analysis

M Hajifoghaha, SH Teshnizi, S Forouhari… - BMC Endocrine …, 2022 - Springer
Background Preeclampsia is a life-threatening disorder during pregnancy and postpartum
periods. Preeclampsia can affect the activity of many organs. It is very important because if …

Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans

H Verloop, OM Dekkers, RP Peeters… - European journal of …, 2014 - academic.oup.com
Iodothyronine deiodinases represent a family of selenoproteins involved in peripheral and
local homeostasis of thyroid hormone action. Deiodinases are expressed in multiple organs …

Genetics of thyroid function

M Medici, TJ Visser, RP Peeters - Best practice & research Clinical …, 2017 - Elsevier
Recent studies show that subtle variations in thyroid function, including subclinical thyroid
dysfunction, and even variation in thyroid function within the normal range, are associated …

ROC 曲线分析妊娠相关血浆蛋白A, 游离雌三醇, β-人绒毛膜促性腺激素对子痫前期的诊断价值

杨斌, 张建武 - 蚌埠医学院学报, 2018 - xuebao.bbmc.edu.cn
目的: 探讨妊娠相关血浆蛋白A (PAPP-A), 游离雌三醇(fE3), β-人绒毛膜促性腺激素(β-hCG)
对子痫前期的预测价值. 方法: 将117 例妊娠期高血压孕妇分为子痫前期组49 …

Polymorphisms of placental iodothyronine deiodinase genes in a rural area of Northern China with high prevalence of neural tube defects

F Wang, YH Gu, J Guo, YH Bao, ZY Qiu, P Zheng… - Human Heredity, 2023 - karger.com
Introduction: We have reported that high total homocysteine and the coexistence of
inadequate thyroid hormones in maternal serum increase the risk of fetal neural tube defects …

[PDF][PDF] An association study of genetic polymorphism of TSHR D727E with hypothyroidism: a study from central India

N Singh, U Singh, A Saxena - Int J Biol Res, 2017 - academia.edu
In present investigation, we conducted a case control-based genetic screening of single
nucleotide polymorphisms (SNPs) loci in TSHR gene with the aim to explore the relationship …

Thyroid Genetics and the Cardiovascular System

A Kuś, A Teumer, L Chaker, M Medici - Thyroid and Heart: A …, 2020 - Springer
Genetic factors are major determinants of thyroid function, and in the last two decades
association studies have identified many genetic variants which are associated with thyroid …

Polimorfisme Gen Iodotironin Deiodinase Tipe 1 (D1) Dan Kadar Hormon Tiroid Pada Wanita Usia Subur Di Daerah Endemik Gaki

SN Wahyuningrum, RA Wibowo - Indonesian Journal of …, 2017 - media.neliti.com
ABSTRAK Latar Belakang. Iodotironin Deiodinase tipe 1 (D1) merupakan selenodeiodinase
yang mempunyai peran ganda dalam aktivasi hormon tiroid menjadi bentuk T3 dan …