Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Biofilm of Candida albicans: formation, regulation and resistance
R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …
range from mucous membranes to systemic infections. The present article provides an …
Amphotericin B and other polyenes—Discovery, clinical use, mode of action and drug resistance
Although polyenes were the first broad spectrum antifungal drugs on the market, after 70
years they are still the gold standard to treat a variety of fungal infections. Polyenes such as …
years they are still the gold standard to treat a variety of fungal infections. Polyenes such as …
Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment
MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …
in hospitalized and immunocompromised or critically ill patients. A limited number of …
Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants
J Branco, IM Miranda, AG Rodrigues - Journal of Fungi, 2023 - mdpi.com
Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …
Southern Europe, and Latin America and is often involved in invasive infections that …
Pathogenesis of Candida albicans biofilm
C Tsui, EF Kong, MA Jabra-Rizk - FEMS Pathogens and …, 2016 - academic.oup.com
Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …
Emerging threats in antifungal-resistant fungal pathogens
D Sanglard - Frontiers in medicine, 2016 - frontiersin.org
The use of antifungal drugs in the therapy of fungal diseases can lead to the development of
antifungal resistance. Resistance has been described for virtually all antifungal agents in …
antifungal resistance. Resistance has been described for virtually all antifungal agents in …
Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents
GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …
immune system of the host fails. Candida albicans is the most important and prevalent …
Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens
E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …
medical concern. In developed countries, the incidence of Candida infections is increasing …
[HTML][HTML] The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris
Highlights•C. auris exhibits resistance to multiple antifungal agents and represents a public
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …