Humans are exposed to microplastics (MPs) daily via ingestion and inhalation. It is not
known whether this results in adverse health effects and, if so, at what levels of exposure …

Nowadays, orthodontic treatment has become increasingly popular. However, the biological
mechanisms of orthodontic tooth movement (OTM) have not been fully elucidated. We were …

Prebiotics are substrates selectively metabolized by hindgut microorganisms conferring
health benefits. Recent studies suggest polyphenols as candidate to prebiotics. Thus, this …

Animal models have provided invaluable information in the pursuit of medical knowledge
and alleviation of human suffering. The foundations of our basic understanding of disease …

Methodological quality (risk of bias) assessment is an important step before study initiation
usage. Therefore, accurately judging study type is the first priority, and the choosing proper …

Background Flavonoids are a class of compounds with a wide variety of biological functions,
being an important source of new products with pharmaceutical potential, including …

Objective To systematically review the methodological assessment tools for pre‐clinical and
clinical studies, systematic review and meta‐analysis, and clinical practice guideline …

Background Animal studies show that peripheral inflammatory stimuli may activate
microglial cells in the brain implicating an important role for microglia in sepsis-associated …

Background The pharmacology, toxicology and pharmacokinetics of bioactive preparations
derived from natural sources has become a flourishing field of research. However …

We report a systematic review and meta-analysis of studies that assessed the
antinociceptive efficacy of cannabinoids, cannabis-based medicines, and endocannabinoid …