[HTML][HTML] Local immune recognition of trophoblast in early human pregnancy: controversies and questions

A Moffett, N Shreeve - Nature Reviews Immunology, 2023 - nature.com
The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …

[HTML][HTML] Vascular changes in the cycling and early pregnant uterus

N Massri, R Loia, JL Sones, R Arora, NC Douglas - JCI insight, 2023 - ncbi.nlm.nih.gov
Uterine vascular remodeling is intrinsic to the cycling and early pregnant endometrium.
Maternal regulatory factors such as ovarian hormones, VEGF, angiopoietins, Notch, and …

[HTML][HTML] Early human trophoblast development: from morphology to function

M Gauster, G Moser, S Wernitznig, N Kupper… - Cellular and Molecular …, 2022 - Springer
Human pregnancy depends on the proper development of the embryo prior to implantation
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …

[HTML][HTML] Advances in cellulose-based hydrogels for biomedical engineering: a review summary

P Zou, J Yao, YN Cui, T Zhao, J Che, M Yang, Z Li… - Gels, 2022 - mdpi.com
In recent years, hydrogel-based research in biomedical engineering has attracted more
attention. Cellulose-based hydrogels have become a research hotspot in the field of …

Advanced strategies in the application of gelatin-based bioink for extrusion bioprinting

J Yang, H He, D Li, Q Zhang, L Xu, C Ruan - Bio-Design and …, 2023 - Springer
The significance of bioink suitability for the extrusion bioprinting of tissue-like constructs
cannot be overemphasized. Gelatin, derived from the hydrolysis of collagen, not only can …

[HTML][HTML] Modelling human placental villous development: designing cultures that reflect anatomy

JL James, A Lissaman, YNS Nursalim… - Cellular and Molecular …, 2022 - Springer
The use of in vitro tools to study trophoblast differentiation and function is essential to
improve understanding of normal and abnormal placental development. The relative …

[HTML][HTML] Human uterine natural killer cells regulate differentiation of extravillous trophoblast early in pregnancy

Q Li, A Sharkey, M Sheridan, E Magistrati… - Cell Stem Cell, 2024 - cell.com
In humans, balanced invasion of trophoblast cells into the uterine mucosa, the decidua, is
critical for successful pregnancy. Evidence suggests that this process is regulated by uterine …

Generation of Human Endometrial Assembloids with a Luminal Epithelium using Air–Liquid Interface Culture Methods

J Tian, J Yang, T Chen, Y Yin, N Li, Y Li… - Advanced …, 2023 - Wiley Online Library
The endometrial lining of the uterus is essential for women's reproductive health and
consists of several different types of epithelial and stromal cells. Although models such as …

Rational design of nanomedicine for placental disorders: birthing a new era in women's reproductive health

HC Geisler, HC Safford, MJ Mitchell - Small, 2023 - Wiley Online Library
The placenta is a transient organ that forms during pregnancy and acts as a biological
barrier, mediating exchange between maternal and fetal circulation. Placental disorders …

Microfluidic high-throughput 3D cell culture

J Ko, D Park, J Lee, S Jung, K Baek, KE Sung… - Nature Reviews …, 2024 - nature.com
High-throughput 3D microfluidic cell culture systems can be designed to model aspects of
human tissues and organs and may thus serve as non-clinical evaluation tools. They benefit …