Tumor markers are substances produced by the tumors or by other cells of the body in
response to cancer or certain benign conditions. Although most of these markers are made …

Breast cancer (BC) is known to be a highly heterogeneous disease that is clinically
subdivided into four primary molecular subtypes, each having distinct morphology and …

The murine epidermis with its hair follicles represents an invaluable model system for tissue
regeneration and stem cell research. Here we used single-cell RNA-sequencing to reveal …

Ubiquitin–proteasome system (UPS) is a selective proteolytic system that is associated with
the expression or function of target proteins and participates in various physiological and …

Treatments targeting oncogenic fusion proteins are notable examples of successful drug
development. Abnormal splicing of genes resulting in fusion proteins is a critical driver of …

Multidrug resistance (MDR) hinders treatment efficacy in cancer therapy. One typical
mechanism contributing to MDR is the overexpression of permeability-glycoprotein (P-gp) …

Circadian disruption has been linked to cancer development, progression, and radiation
response. Clinical evidence to date shows that circadian genetic variation and time of …

Background Metastasis is responsible for a significant number of breast cancer-related
deaths. Hypoxia, a primary driving force of cancer metastasis, induces the expression of …

Recent research has emphasized the interaction between the circadian clock and lipid
metabolism, particularly in relation to tumors. This review aims to explore how the circadian …

Triple‐negative breast cancer (TNBC) lacks expression of estrogen receptor (ER),
progesterone receptor, and the HER 2 receptor; it is highly proliferative and becomes the …