Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants

J Raphel, M Holodniy, SB Goodman, SC Heilshorn - Biomaterials, 2016 - Elsevier
The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Hip arthroplasty

R Pivec, AJ Johnson, SC Mears, MA Mont - The Lancet, 2012 - thelancet.com
Total hip arthroplasty is a cost-effective surgical procedure undertaken to relieve pain and
restore function to the arthritic hip joint. More than 1 million arthroplasties are done every …

Current epidemiology of revision total hip arthroplasty in the United States: national inpatient sample 2009 to 2013

CU Gwam, JB Mistry, NS Mohamed, M Thomas… - The Journal of …, 2017 - Elsevier
Background Despite the excellent outcomes associated with primary total hip arthroplasty
(THA), implant failure and revision continues to burden the healthcare system. THA failure …

Antibacterial surface design of biomedical titanium materials for orthopedic applications

Z Yuan, Y He, C Lin, P Liu, K Cai - Journal of Materials Science & …, 2021 - Elsevier
Titanium (Ti) and titanium alloys have become widely used as biomedical materials in
orthopedics because of their good machinability, corrosion resistance, low elastic modulus …

Bioceramic composites for orthopaedic applications: A comprehensive review of mechanical, biological, and microstructural properties

D Shekhawat, A Singh, MK Banerjee, T Singh… - Ceramics …, 2021 - Elsevier
Bioceramics have been widely utilized for orthopaedic applications in which the
biocompatibility and mechanical properties of the materials are vital characteristics to be …

Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge

W Xi, V Hegde, SD Zoller, HY Park, CM Hart… - Nature …, 2021 - nature.com
Implant related infections are the most common cause of joint arthroplasty failure, requiring
revision surgeries and a new implant, resulting in a cost of $8.6 billion annually. To address …

Implant materials and prosthetic joint infection: the battle with the biofilm

DJ Davidson, D Spratt, AD Liddle - EFORT open reviews, 2019 - eor.bioscientifica.com
Prosthetic joint infection (PJI) is associated with poor clinical outcomes and is expensive to
treat. Although uncommon overall (affecting between 0.5% and 2.2% of cases), PJI is one of …

Twenty common errors in the diagnosis and treatment of periprosthetic joint infection

C Li, N Renz, A Trampuz, C Ojeda-Thies - International orthopaedics, 2020 - Springer
Background Misconceptions and errors in the management of periprosthetic joint infection
(PJI) can compromise the treatment success. The goal of this paper is to systematically …

Prevention of periprosthetic joint infection: new guidelines

J Parvizi, N Shohat, T Gehrke - The bone & joint journal, 2017 - boneandjoint.org.uk
The World Health Organization (WHO) and the Centre for Disease Control and Prevention
(CDC) recently published guidelines for the prevention of surgical site infection. The WHO …

Risk factors associated with surgical site infection in 30 491 primary total hip replacements

RS Namba, MCS Inacio… - The Journal of Bone & …, 2012 - boneandjoint.org.uk
We examined patient and surgical factors associated with deep surgical site infection (SSI)
following total hip replacement (THR) in a large integrated healthcare system. A …