Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

Flu is a serious health, medical, and economic problem, but no therapy is yet available that
has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after …

These clinical practice guidelines are an update of the guidelines published by the
Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza …

Background Baloxavir marboxil (hereafter baloxavir), a selective inhibitor of influenza cap-
dependent endonuclease, was approved in 2018 in the USA and Japan for the treatment of …

Background Despite widespread use, questions remain about the efficacy of oseltamivir in
the treatment of influenza. We aimed to do an individual patient data meta-analysis for all …

Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

Background Neuraminidase inhibitors were widely used during the 2009–10 influenza A
H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We …

Objective To evaluate risk factors for severe outcomes in patients with seasonal and
pandemic influenza. Design Systematic review. Study selection Observational studies …

Background Neuraminidase inhibitors (NIs) are stockpiled and recommended by public
health agencies for treating and preventing seasonal and pandemic influenza. They are …

Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …