Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and
nonvertebrate organisms that mediates diverse biological actions and demonstrates …

The brain is composed of many lipids with varied forms that serve not only as structural
components but also as essential signaling molecules. Lysophosphatidic acid (LPA) is an …

Lysophospholipids are cell membrane-derived lipids that include both glycerophospholipids
such as lysophosphatidic acid (LPA) and sphingoid lipids such as sphingosine 1-phosphate …

Lysophosphatidic acid (LPA) is a bioactive phospholipid that is present in all tissues
examined to date. LPA signals extracellularly via cognate G protein-coupled receptors to …

Introduction Identification of blood-based metabolic changes might provide early and easy-
to-obtain biomarkers. Methods We included 127 Alzheimer's disease (AD) patients and 121 …

Background Lysophosphatidic acid (LPA) is a bioactive lipid with a wide biological activity.
Previous studies have shown its potential usefulness as a diagnostic marker for ovarian …

Melanoma is the deadliest form of skin cancer in which patients with metastatic disease
have a 5-year survival rate of less than 10%. Recently, the overexpression of a β …

Apoptosis is an active and tightly regulated form of cell death, which can also be considered
a stress-induced process of cellular communication. Recent studies reveal that the lipid …

Bone marrow contains endothelial progenitor cells (EPCs) that, upon pro-angiogenic stimuli,
migrate and differentiate into endothelial cells (ECs) and contribute to re-endothelialization …

The brain contains various forms of lipids that are important for maintaining its structural
integrity and regulating various signaling cascades. Autotaxin (ATX) is an ecto-nucleotide …