NRF2 in cardiovascular diseases: a ray of hope!
R Vashi, BM Patel - Journal of cardiovascular translational research, 2021 - Springer
Heart failure is a worldwide pandemic influencing 26 million individuals worldwide and is
expanding. Imbalanced redox homeostasis in cardiac cells alters the structure and function …
expanding. Imbalanced redox homeostasis in cardiac cells alters the structure and function …
[HTML][HTML] The role of heme oxygenase-1 in remote ischemic and anesthetic organ conditioning
I Bauer, A Raupach - Antioxidants, 2019 - mdpi.com
The cytoprotective effects of the heme oxygenase (HO) pathway are widely acknowledged.
These effects are mainly mediated by degradation of free, pro-oxidant heme and the …
These effects are mainly mediated by degradation of free, pro-oxidant heme and the …
Propofol‐induced miR‐219‐5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3‐mediated Wnt/β‐catenin signalling activation
T Gong, X Ning, Z Deng, M Liu, B Zhou… - Journal of Cellular …, 2019 - Wiley Online Library
Propofol is one of the most extensively used intravenous anaesthetic agents, which has
been found to improve the surgical intervention outcome of several types of cancer …
been found to improve the surgical intervention outcome of several types of cancer …
Propofol protects cardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling …
Z Lu, Z Liu, B Fang - Bioengineered, 2022 - Taylor & Francis
Propofol offers important protective effects in ischemia/reperfusion-induced cardiomyocyte
injury, but its specific mechanisms in doxorubicin (DOX)-induced cardiotoxicity have not …
injury, but its specific mechanisms in doxorubicin (DOX)-induced cardiotoxicity have not …
Effect of propofol on the production of inflammatory cytokines by human polarized macrophages
T Kochiyama, X Li, H Nakayama, M Kage… - Mediators of …, 2019 - Wiley Online Library
Macrophages are key immune system cells involved in inflammatory processes. Classically
activated (M1) macrophages are characterized by strong antimicrobicidal properties …
activated (M1) macrophages are characterized by strong antimicrobicidal properties …
Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway
W Sun, Z Wang, M Sun, W Huang, Y Wang… - Cell and Tissue …, 2021 - Springer
Myocardial ischemia/reperfusion injury (I/RI) frequently incurs in acute myocardial infarction
with high morbidity and mortality worldwide and is characterized with cardiomyocyte …
with high morbidity and mortality worldwide and is characterized with cardiomyocyte …
[PDF][PDF] Protective effects of trimetazidine and coenzyme Q10 on cisplatin-induced cardiotoxicity by alleviating oxidative stress and mitochondrial dysfunction.
L Zhao - Anatolian Journal of Cardiology/Anadolu Kardiyoloji …, 2019 - jag.journalagent.com
Objective: The objective of this study was to investigate the effects of trimetazidine (TMZ) and
coenzyme Q10 (CoQ10) on cisplatin-induced cardiotoxicity in rat cardiomyocytes. Methods …
coenzyme Q10 (CoQ10) on cisplatin-induced cardiotoxicity in rat cardiomyocytes. Methods …
[HTML][HTML] Exon skipping induced by CRISPR-directed gene editing regulates the response to chemotherapy in non-small cell lung carcinoma cells
K Banas, S Modarai, N Rivera-Torres, BC Yoo… - Gene therapy, 2022 - nature.com
We have been developing CRISPR-directed gene editing as an augmentative therapy for
the treatment of non-small cell lung carcinoma (NSCLC) by genetic disruption of Nuclear …
the treatment of non-small cell lung carcinoma (NSCLC) by genetic disruption of Nuclear …
[HTML][HTML] Effects of prolonged dietary curcumin exposure on skeletal muscle biochemical and functional responses of aged male rats
Oxidative stress resulting from decreased antioxidant protection and increased reactive
oxygen and nitrogen species (RONS) production may contribute to muscle mass loss and …
oxygen and nitrogen species (RONS) production may contribute to muscle mass loss and …
Acute administration of the olive constituent, oleuropein, combined with ischemic postconditioning increases myocardial protection by modulating oxidative defense
M Tsoumani, A Georgoulis, PE Nikolaou… - Free Radical Biology …, 2021 - Elsevier
Oleuropein, one of the main polyphenolic constituents of olive, is cardioprotective against
ischemia reperfusion injury (IRI). We aimed to assess the cardioprotection afforded by acute …
ischemia reperfusion injury (IRI). We aimed to assess the cardioprotection afforded by acute …