The completion of the Human Genome Project lays a foundation for systematically studying
the human genome from evolutionary history to precision medicine against diseases. With …

As an important post-translational modification (PTM), protein phosphorylation is involved in
the regulation of almost all of biological processes in eukaryotes. Due to the rapid progress …

Post-translational modifications (PTMs) occurring at protein lysine residues, or protein lysine
modifications (PLMs), play critical roles in regulating biological processes. Due to the …

Post-translational modifications (PTMs) are critical molecular mechanisms that regulate
protein functions temporally and spatially in various organisms. Since most PTMs are …

Protein phosphorylation, one of the main protein post-translational modifications, is required
for regulating various life activities. Kinases and phosphatases that regulate protein …

As a crucial molecular mechanism, post-translational modifications (PTMs) play critical roles
in a wide range of biological processes in plants. Recent advances in mass spectrometry …

As one of the most important reversible types of post-translational modification, protein
methylation catalyzed by methyltransferases carries many pivotal biological functions as …

Regulators of G protein signaling (RGS) proteins modulate the physiologic actions of many
neurotransmitters, hormones, and other signaling molecules. Human RGS proteins …

Protein phosphorylation is one of the most important post-translational modifications (PTMs)
and regulates a broad spectrum of biological processes. Recent progresses in …

Temporal and spatial protein phosphorylation dynamically orchestrates a broad spectrum of
biological processes and plays various physiological and pathological roles in diseases and …