Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

EA Kearney, PA Agius, V Chaumeau, JC Cutts… - Elife, 2021 - elifesciences.org
Background: Entomological surveillance for malaria is inherently resource-intensive and
produces crude population-level measures of vector exposure which are insensitive in low …

Children as biomarker orphans: progress in the field of pediatric biomarkers

DR Shores, AD Everett - The Journal of pediatrics, 2018 - jpeds.com
Biomarkers are incorporated ubiquitously into clini-cal practice as surrogate endpoints of
physiologic and pathologic processes that cannot be measured directly. For example, a lipid …

Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure

V Yman, J Tuju, MT White, G Kamuyu, K Mwai… - Nature …, 2022 - nature.com
Strengthening malaria surveillance is a key intervention needed to reduce the global
disease burden. Reliable serological markers of recent malaria exposure could improve …

The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria …

H Lamptey, MF Ofori, KA Kusi, B Adu, E Owusu-Yeboa… - Malaria journal, 2018 - Springer
Background The gametocyte stage of Plasmodium falciparum is considered an important
target for disrupting malaria transmission. Indications are that various demographic groups …

[HTML][HTML] Antibody acquisition models: a new tool for serological surveillance of malaria transmission intensity

V Yman, MT White, J Rono, B Arcà, FH Osier… - Scientific reports, 2016 - nature.com
Serology has become an increasingly important tool for the surveillance of a wide range of
infectious diseases. It has been particularly useful to monitor malaria transmission in …

Serological markers to measure recent changes in malaria at population level in Cambodia

K Kerkhof, V Sluydts, L Willen, S Kim, L Canier, S Heng… - Malaria journal, 2016 - Springer
Background Serological markers for exposure to different Plasmodium species have
recently been used in multiplex immunoassays based on the Luminex technology. However …

Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202. 11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic …

B Adu, MK Cherif, S Bosomprah, A Diarra, FKN Arthur… - Malaria journal, 2016 - Springer
Background Differences in parasite transmission intensity influence the process of
acquisition of host immunity to Plasmodium falciparum malaria and ultimately, the rate of …

Plasmodium falciparum and helminth coinfections increase IgE and parasite-specific IgG responses

R Santano, R Rubio, B Grau-Pujol, V Escola… - Microbiology …, 2021 - Am Soc Microbiol
Coinfection with Plasmodium falciparum and helminths may impact the immune response to
these parasites because they induce different immune profiles. We studied the effects of …

Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

LE Amoah, FK Acquah, R Ayanful-Torgby, A Oppong… - Parasites & vectors, 2018 - Springer
Abstract Background During a Plasmodium infection, exposure of human host immune cells
to both the asexual and the sexual stages of the parasite elicit immune responses. These …

Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites: Naturally Acquired Humoral Immune Response and B-Cell Epitope Mapping in Brazilian …

RN Rodrigues-da-Silva, IF Soares… - Frontiers in …, 2017 - frontiersin.org
The cell-traversal protein for ookinetes and sporozoites (CelTOS), a highly conserved
antigen involved in sporozoite motility, plays an important role in the traversal of host cells …