Pathogenicity and virulence of Clostridium botulinum

AM Rawson, AW Dempster, CM Humphreys… - Virulence, 2023 - Taylor & Francis
Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by
their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor …

Foodborne botulism: clinical diagnosis and medical treatment

D Lonati, A Schicchi, M Crevani, E Buscaglia… - Toxins, 2020 - mdpi.com
Botulinum neurotoxins (BoNTs) produced by Clostridia species are the most potent
identified natural toxins. Classically, the toxic neurological syndrome is characterized by an …

Current trends in the biosensors for biological warfare agents assay

M Pohanka - Materials, 2019 - mdpi.com
Biosensors are analytical devices combining a physical sensor with a part of biological
origin providing sensitivity and selectivity toward analyte. Biological warfare agents are …

Multiplex biosensing based on highly sensitive magnetic nanolabel quantification: rapid detection of botulinum neurotoxins A, B, and E in liquids

AV Orlov, SL Znoyko, VR Cherkasov… - Analytical …, 2016 - ACS Publications
We present a multiplex quantitative lateral flow (LF) assay for simultaneous on-site detection
of botulinum neurotoxin (BoNT) types A, B, and E in complex matrixes, which is innovative …

A colorimetric aptasensor based on gold nanoparticles for detection of microbial toxins: an alternative approach to conventional methods

GS Geleta - Analytical and Bioanalytical Chemistry, 2022 - Springer
Frequent contamination of foods with microbial toxins produced by microorganisms such as
bacteria, fungi, and algae represents an increasing public health problem that requires the …

Magnetic nanoseparation technology for efficient control of microorganisms and toxins in foods: a Review

Y Kang, S Shi, H Sun, J Dan, Y Liang… - Journal of Agricultural …, 2022 - ACS Publications
Outbreaks of foodborne diseases mediated by food microorganisms and toxins remain one
of the leading causes of disease and death worldwide. It not only poses a serious threat to …

Rapid detection of botulinum neurotoxins—A review

RJ Hobbs, CA Thomas, J Halliwell, CD Gwenin - Toxins, 2019 - mdpi.com
A toxin is a poisonous substance produced within living cells or organisms. One of the most
potent groups of toxins currently known are the Botulinum Neurotoxins (BoNTs). These are …

Botulinum neurotoxin detection methods for public health response and surveillance

N Thirunavukkarasu, E Johnson, S Pillai… - … in bioengineering and …, 2018 - frontiersin.org
Botulism outbreak due to consumption of food contaminated with botulinum neurotoxins
(BoNTs) is a public health emergency. The threat of bioterrorism through deliberate …

The electrochemical detection of bioterrorism agents: a review of the detection, diagnostics, and implementation of sensors in biosafety programs for Class A …

C O'Brien, K Varty, A Ignaszak - Microsystems & Nanoengineering, 2021 - nature.com
During the past year, disease has shown us the iron grip it can hold over a population of
people. Health systems can be overwhelmed, economies can be brought into recession …

Fast, ratiometric FRET from quantum dot conjugated stabilized single chain variable fragments for quantitative botulinum neurotoxin sensing

J Lee, MB Brennan, R Wilton, CE Rowland… - Nano …, 2015 - ACS Publications
Botulinum neurotoxin (BoNT) presents a significant hazard under numerous realistic
scenarios. The standard detection scheme for this fast-acting toxin is a lab-based mouse …