Plasmodium species: master renovators of their host cells
Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …
strategies that they use to survive and thrive within different intracellular environments …
Malaria parasite proteins that remodel the host erythrocyte
Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
erythrocyte membrane and induce substantial changes in the morphology, physiology and …
STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting
Variant surface antigens play an important role in Plasmodium falciparum malaria
pathogenesis and in immune evasion by the parasite. Although most work to date has …
pathogenesis and in immune evasion by the parasite. Although most work to date has …
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
A Claessens, Y Adams, A Ghumra… - Proceedings of the …, 2012 - National Acad Sciences
Cerebral malaria is the most deadly manifestation of infection with Plasmodium falciparum.
The pathology of cerebral malaria is characterized by the accumulation of infected …
The pathology of cerebral malaria is characterized by the accumulation of infected …
Revisiting gametocyte biology in malaria parasites
P Ngotho, AB Soares, F Hentzschel… - FEMS microbiology …, 2019 - academic.oup.com
Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito
vector. They are present at low levels in blood circulation and significant knowledge gaps …
vector. They are present at low levels in blood circulation and significant knowledge gaps …
Identification of New PNEPs Indicates a Substantial Non-PEXEL Exportome and Underpins Common Features in Plasmodium falciparum Protein Export
A Heiber, F Kruse, C Pick, C Grüring… - PLoS …, 2013 - journals.plos.org
Malaria blood stage parasites export a large number of proteins into their host erythrocyte to
change it from a container of predominantly hemoglobin optimized for the transport of …
change it from a container of predominantly hemoglobin optimized for the transport of …
Red blood cell invasion by the malaria parasite is coordinated by the PfAP2-I transcription factor
Obligate intracellular parasites must efficiently invade host cells in order to mature and be
transmitted. For the malaria parasite Plasmodium falciparum, invasion of host red blood cells …
transmitted. For the malaria parasite Plasmodium falciparum, invasion of host red blood cells …
Plasmodium Nesting: Remaking the Erythrocyte from the Inside Out
One of the most fascinating and remarkable features of Plasmodium parasites, which cause
malaria, is their choice of erythrocytes as the principal host cells in which to reside during …
malaria, is their choice of erythrocytes as the principal host cells in which to reside during …
Maurer's clefts, the enigma of Plasmodium falciparum
E Mundwiler-Pachlatko… - Proceedings of the …, 2013 - National Acad Sciences
Plasmodium falciparum, the causative agent of malaria, completely remodels the infected
human erythrocyte to acquire nutrients and to evade the immune system. For this process …
human erythrocyte to acquire nutrients and to evade the immune system. For this process …