Recently reported mature survival data have confirmed the favorable prognosis in
polycythemia vera (PV), with an estimated median survival of 24 years, in patients younger …

1Centre for Medical Education, Queen's University, Belfast, 2MRC Molecular Haematology
Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine …

Under the auspices of an International Working Group, seven centers submitted diagnostic
and follow-up information on 1545 patients with World Health Organization-defined …

Aquagenic pruritus (AP) is a symptom typical for polycythemia vera, but very little is known
about its exact frequency, characteristics, influence on quality of life, and proper treatment …

Eur J Clin Invest 2010; 40 (9): 828–834 Abstract Background Pruritus is a defining feature of
polycythemia vera (PV) and is seen in approximately 40% of patients. In most cases, the …

Pruritus is a common symptom in patients with Philadelphia chromosome–negative
myeloproliferative disorders (MPDs). The pathophysiology of MPD-associated pruritus is …

Genetic studies in the past decade have improved our understanding of the molecular basis
of the BCR-ABL1-negative myeloproliferative neoplasm (MPN) polycythaemia vera (PV) …

Objectives: Describe the typical presenting features of polycythemia. Outline the
management of polycythemia. Review the potential complications of polycythemia. Use …

Pruritus, as one of the most common clinical manifestations in medicine, has been
recognized for many centuries. Defined as an unpleasant sensation resulting in the need to …

Background Pruritus is a frequent symptom experienced by patients with myeloproliferative
neoplasms (MPN). Aquagenic pruritus (AP) is the most common type. The Myeloproliferative …