Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem

SJ Rogerson, M Desai, A Mayor, E Sicuri… - The Lancet infectious …, 2018 - thelancet.com
Over the past 10 years, knowledge of the burden, economic costs, and consequences of
malaria in pregnancy has improved, and the prevalence of malaria caused by Plasmodium …

Fusobacterium nucleatum and cancer

T Alon‐Maimon, O Mandelboim… - Periodontology …, 2022 - Wiley Online Library
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is
involved in the progression of an increasing number of tumors types. Thus far, the …

First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

B Mordmüller, M Sulyok, D Egger-Adam… - Clinical Infectious …, 2019 - academic.oup.com
Background Malaria in pregnancy has major impacts on mother and child health. To
complement existing interventions, such as intermittent preventive treatment and use of …

New insights into malaria pathogenesis

CA Moxon, MP Gibbins, D McGuinness… - Annual Review of …, 2020 - annualreviews.org
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

MØ Agerbæk, SR Bang-Christensen, MH Yang… - Nature …, 2018 - nature.com
Isolation of metastatic circulating tumor cells (CTCs) from cancer patients is of high value for
disease monitoring and molecular characterization. Despite the development of many new …

The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

TD Ahrens, SR Bang-Christensen… - Frontiers in cell and …, 2020 - frontiersin.org
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …

An overview of malaria in pregnancy

M Bauserman, AL Conroy, K North, J Patterson… - Seminars in …, 2019 - Elsevier
One hundred twenty-five million pregnant women are at risk for contracting malaria, a
preventable cause of maternal and infant morbidity and death. Malaria parasites contribute …

[HTML][HTML] Placental colonization by Fusobacterium nucleatum is mediated by binding of the Fap2 lectin to placentally displayed Gal-GalNAc

L Parhi, J Abed, A Shhadeh, T Alon-Maimon, S Udi… - Cell Reports, 2022 - cell.com
While the existence of an indigenous placental microbiota remains controversial, several
pathogens are known to be involved in adverse pregnancy outcomes. Fusobacterium …

Platelet membrane-coated and VAR2CSA malaria protein-functionalized nanoparticles for targeted treatment of primary and metastatic cancer

M Zhou, W Lai, G Li, F Wang, W Liu, J Liao… - … Applied Materials & …, 2021 - ACS Publications
Metastasis is the main cause of death in cancer patients. The efficacy of pharmacological
therapy for cancer is limited by the heterogeneous nature of cancer cells and the lack of …

Host-parasite interactions during Plasmodium infection: Implications for immunotherapies

P Chandley, R Ranjan, S Kumar, S Rohatgi - Frontiers in Immunology, 2023 - frontiersin.org
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …