By averaging over atomic details, coarse-grained (CG) models provide profound
computational and conceptual advantages for studying soft materials. In particular, bottom …

The traditional computational modeling of protein structure, dynamics, and interactions
remains difficult for many protein systems. It is mostly due to the size of protein …

In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding proteins into stress
granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels …

By focusing on essential features, while averaging over less important details, coarse-
grained (CG) models provide significant computational and conceptual advantages with …

A longstanding question in molecular biology is the extent to which the behavior of
macromolecules observed in vitro accurately reflects their behavior in vivo. A number of …

Rational peptide design and large-scale prediction of peptide structure from sequence
remain a challenge for chemical biologists. We present PEP-FOLD, an online service, aimed …

Venezuelan equine encephalitis virus (VEEV), a member of the membrane‐containing
Alphavirus genus, is a human and equine pathogen, and has been developed as a …

Protein–peptide interactions play essential functional roles in living organisms and their
structural characterization is a hot subject of current experimental and theoretical research …

Three basic proline-rich salivary proteins have been produced through the recombinant
route. IB5 is a small basic proline-rich protein that is involved in the binding of plant tannins …

During chronic liver disease, tissue remodeling leads to dramatic changes and
accumulation of matrix components. Matrix metalloproteases and their inhibitors have been …