Diagnosis and treatment of metastatic colorectal cancer: a review

LH Biller, D Schrag - Jama, 2021 - jamanetwork.com
Importance Colorectal cancer (CRC) is the third most common cause of cancer mortality
worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new …

Colorectal liver metastasis: molecular mechanism and interventional therapy

H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

A Cervantes, R Adam, S Roselló, D Arnold… - Annals of …, 2023 - annalsofoncology.org
Colorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new
cases per year, and is the second leading cause of cancer death. 1 CRC occurs more …

[HTML][HTML] Treatment of metastatic colorectal cancer: ASCO guideline

VK Morris, EB Kennedy, NN Baxter… - Journal of clinical …, 2023 - ncbi.nlm.nih.gov
Treatment of Metastatic Colorectal Cancer: ASCO Guideline - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Colon cancer, version 2.2021, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2021 - jnccn.org
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Colon Cancer focuses on systemic therapy options for the treatment of metastatic …

Fasting-mimicking diet is safe and reshapes metabolism and antitumor immunity in patients with cancer

C Vernieri, G Fucà, F Ligorio, V Huber, A Vingiani… - Cancer Discovery, 2022 - AACR
In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of
antineoplastic treatments by modulating systemic metabolism and boosting antitumor …

Individual patient data meta-analysis of FOLFOXIRI plus bevacizumab versus doublets plus bevacizumab as initial therapy of unresectable metastatic colorectal …

C Cremolini, C Antoniotti, A Stein, J Bendell… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE A proper estimation of the magnitude of the overall survival (OS) benefit from
infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) plus …

Survival improvement for patients with metastatic colorectal cancer over twenty years

FA Zeineddine, MA Zeineddine, A Yousef, Y Gu… - NPJ Precision …, 2023 - nature.com
Over the past two decades of successive clinical trials in metastatic colorectal cancer (CRC),
the median overall survival of both control and experimental arms has steadily improved …

Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open …

C Antoniotti, D Rossini, F Pietrantonio… - The Lancet …, 2022 - thelancet.com
Background Immune checkpoint inhibitors have not shown clinical benefit to patients with
metastatic colorectal cancer who had proficient mismatch repair (pMMR) or microsatellite …

[HTML][HTML] Management of BRAF-mutant metastatic colorectal cancer: a review of treatment options and evidence-based guidelines

A Grothey, M Fakih, J Tabernero - Annals of Oncology, 2021 - Elsevier
Background Colorectal cancer (CRC) is still a leading cause of cancer-related deaths in the
United States and worldwide, despite recent improvements in cancer management. CRC …