[HTML][HTML] Epigenetic regulators controlling osteogenic lineage commitment and bone formation
Bone formation and homeostasis are controlled by environmental factors and endocrine
regulatory cues that initiate intracellular signaling pathways capable of modulating gene …
regulatory cues that initiate intracellular signaling pathways capable of modulating gene …
Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts
ME Carrasco, R Thaler, G Nardocci… - Journal of Biological …, 2023 - ASBMB
Bivalent epigenomic regulatory domains containing both activating histone 3 lysine 4
(H3K4me3) and repressive lysine 27 (H3K27me3) trimethylation are associated with key …
(H3K4me3) and repressive lysine 27 (H3K27me3) trimethylation are associated with key …
[HTML][HTML] Protein arginine methyltransferases PRMT1, PRMT4/CARM1 and PRMT5 have distinct functions in control of osteoblast differentiation
Osteogenic differentiation of mesenchymal cells is controlled by epigenetic enzymes that
regulate post-translational modifications of histones. Compared to acetyl or …
regulate post-translational modifications of histones. Compared to acetyl or …
[HTML][HTML] Effect of local administration of doxycycline on bone regeneration/formation: a systematic review
TC Dotta, M Chang, H Parize, FAT de Figueiredo… - Dentistry Review, 2024 - Elsevier
Objective To evaluate the effects of local administration of doxycycline on bone regeneration
and formation. Design An electronic search was conducted in the PubMed, EMBASE …
and formation. Design An electronic search was conducted in the PubMed, EMBASE …
G-protein coupled receptor 5C (GPRC5C) is required for osteoblast differentiation and responds to EZH2 inhibition and multiple osteogenic signals
Osteoblast differentiation is epigenetically suppressed by the H3K27 methyltransferase
EZH2, and induced by the morphogen BMP2 and transcription factor RUNX2. These factors …
EZH2, and induced by the morphogen BMP2 and transcription factor RUNX2. These factors …
MiR-26b-5p/TET3 regulates the osteogenic differentiation of human bone mesenchymal stem cells and bone reconstruction in female rats with calvarial defects
W Ye, C Zhang, Z Fan - Molecular Biology Reports, 2024 - Springer
Background MicroRNAs (miRNAs) play critical roles in the osteogenic differentiation of
human bone mesenchymal stem cells (hBMSCs), but the mechanism by which miRNAs …
human bone mesenchymal stem cells (hBMSCs), but the mechanism by which miRNAs …