Recent developments and current controversies in depression
KP Ebmeier, C Donaghey, JD Steele - The Lancet, 2006 - thelancet.com
In this review of the last 5 years' developments in research into depression we focus on
recent advances and current controversies. We cover epidemiology and basic science as …
recent advances and current controversies. We cover epidemiology and basic science as …
The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders
DN Jones, MA Raghanti - Journal of Chemical Neuroanatomy, 2021 - Elsevier
Monoamine oxidase enzymes are responsible for the degredation of serotonin, dopamine,
and norepinephrine in the central neurvous system. Although it has been nearly 100 years …
and norepinephrine in the central neurvous system. Although it has been nearly 100 years …
Poor replication of candidate genes for major depressive disorder using genome-wide association data
FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide
association study (GWAS) in major depressive disorder (MDD) were used to explore …
association study (GWAS) in major depressive disorder (MDD) were used to explore …
Gene–environment interaction analysis of serotonin system markers with adolescent depression
We report analyses from a study of gene–environment interaction in adolescent depression.
The sample was selected from 1990 adolescents aged 10–20 years: those with depression …
The sample was selected from 1990 adolescents aged 10–20 years: those with depression …
Meta-analyses of genetic studies on major depressive disorder
S López-León, A Janssens… - Molecular …, 2008 - nature.com
The genetic basis of major depressive disorder (MDD) has been investigated extensively,
but the identification of MDD genes has been hampered by conflicting results from …
but the identification of MDD genes has been hampered by conflicting results from …
Impulsivity, aggression, and serotonin: a molecular psychobiological perspective
KP Lesch, U Merschdorf - Behavioral sciences & the law, 2000 - Wiley Online Library
The expression of aggressiveness, which constitutes many facets of behavior, is influenced
by a complex interaction of biologic, psychologic, and social variables. Even though …
by a complex interaction of biologic, psychologic, and social variables. Even though …
An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences
Y Huang, SP Cate, C Battistuzzi, MA Oquendo… - …, 2004 - nature.com
Monoamine oxidase A (MAOA) activity is altered in mood disorders and lower activity
associated with aggressive behavior. The gene has a functional polymorphism with a …
associated with aggressive behavior. The gene has a functional polymorphism with a …
ADHD co-morbidities: A review of implication of gene× environment effects with dopamine-related genes
ADHD is a major burden in adulthood, where co-morbid conditions such as depression,
substance use disorder and obesity often dominate the clinical picture. ADHD has …
substance use disorder and obesity often dominate the clinical picture. ADHD has …
Toward a molecular architecture of personality
Epidemiological studies provided a large body of evidence that personality dimensions are
influenced by genetic factors and that the genetic component is highly complex, polygenic …
influenced by genetic factors and that the genetic component is highly complex, polygenic …
Reduced amygdala–prefrontal coupling in major depression: association with MAOA genotype and illness severity
U Dannlowski, P Ohrmann, C Konrad… - International Journal …, 2009 - academic.oup.com
The amygdala plays a pivotal role in a cortico-limbic circuitry implicated in emotion
processing and regulation. In the present study, functional connectivity of the amygdala with …
processing and regulation. In the present study, functional connectivity of the amygdala with …