[HTML][HTML] Invited review: The influence of immune activation on transition cow health and performance—A critical evaluation of traditional dogmas

EA Horst, SK Kvidera, LH Baumgard - Journal of Dairy Science, 2021 - Elsevier
The progression from gestation into lactation represents the transition period, and it is
accompanied by marked physiological, metabolic, and inflammatory adjustments. The entire …

The immune system's role in sepsis progression, resolution, and long‐term outcome

MJ Delano, PA Ward - Immunological reviews, 2016 - Wiley Online Library
Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …

Glutamine and cancer: cell biology, physiology, and clinical opportunities

CT Hensley, AT Wasti… - The Journal of clinical …, 2013 - Am Soc Clin Investig
Glutamine is an abundant and versatile nutrient that participates in energy formation, redox
homeostasis, macromolecular synthesis, and signaling in cancer cells. These characteristics …

Metabolic regulation of immune responses

K Ganeshan, A Chawla - Annual review of immunology, 2014 - annualreviews.org
The immune system defends against pathogens and maintains tissue homeostasis for the
life of the organism. These diverse functions are bioenergetically expensive, requiring …

Metabolism of inflammation limited by AMPK and pseudo-starvation

LAJ O'Neill, DG Hardie - Nature, 2013 - nature.com
Metabolic changes in cells that participate in inflammation, such as activated macrophages
and T-helper 17 cells, include a shift towards enhanced glucose uptake, glycolysis and …

More than just protein building blocks: how amino acids and related metabolic pathways fuel macrophage polarization

M Kieler, M Hofmann, G Schabbauer - The FEBS journal, 2021 - Wiley Online Library
Macrophages represent the first line of defence in innate immune responses and
additionally serve important functions for the regulation of host inflammation and tissue …

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

JC Rodríguez-Prados, PG Través, J Cuenca… - The Journal of …, 2010 - journals.aai.org
Macrophages play a relevant role in innate and adaptive immunity depending on the
balance of the stimuli received. From an analytical and functional point of view, macrophage …

The role of diet and gut microbiota in regulating gastrointestinal and inflammatory disease

PA Gill, S Inniss, T Kumagai, FZ Rahman… - Frontiers in …, 2022 - frontiersin.org
Diet is an important lifestyle factor that is known to contribute in the development of human
disease. It is well established that poor diet plays an active role in exacerbating metabolic …

Trade‐offs in evolutionary immunology: just what is the cost of immunity?

RL Lochmiller, C Deerenberg - Oikos, 2000 - Wiley Online Library
It has become increasingly clear that life‐history patterns among the vertebrates have been
shaped by the plethora and variety of immunological risks associated with parasitic faunas …

Amino acids and immune function

P Li, YL Yin, D Li, SW Kim, G Wu - British Journal of Nutrition, 2007 - cambridge.org
A deficiency of dietary protein or amino acids has long been known to impair immune
function and increase the susceptibility of animals and humans to infectious disease …