Strategies to counter antipsychotic-associated weight gain in patients with schizophrenia
W Marteene, K Winckel, S Hollingworth… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Patients living with schizophrenia have a marked risk of clinically significant
weight gain and obesity compared to the general population. The risks have been …
weight gain and obesity compared to the general population. The risks have been …
[HTML][HTML] Preclinical and clinical sex differences in antipsychotic-induced metabolic disturbances: a narrative review of adiposity and glucose metabolism
LN Castellani, KA Costa-Dookhan… - Journal of psychiatry …, 2019 - ncbi.nlm.nih.gov
Antipsychotic (AP) medications are associated with an increased risk of developing
metabolic side effects including weight gain, type 2 diabetes (T2D), dyslipidemia, and …
metabolic side effects including weight gain, type 2 diabetes (T2D), dyslipidemia, and …
Antipsychotics impair regulation of glucose metabolism by central glucose
LN Castellani, S Pereira, C Kowalchuk… - Molecular …, 2022 - nature.com
Hypothalamic detection of elevated circulating glucose triggers suppression of endogenous
glucose production (EGP) to maintain glucose homeostasis. Antipsychotics alleviate …
glucose production (EGP) to maintain glucose homeostasis. Antipsychotics alleviate …
[HTML][HTML] Impaired hormonal regulation of appetite in schizophrenia: a narrative review dissecting intrinsic mechanisms and the effects of antipsychotics
M Lis, B Stańczykiewicz, P Liśkiewicz… - Psychoneuroendocrinology, 2020 - Elsevier
Cardiometabolic diseases are the main contributor of reduced life expectancy in patients
with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important …
with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important …
Brain insulin action: Implications for the treatment of schizophrenia
SM Agarwal, C Kowalchuk, L Castellani… - …, 2020 - Elsevier
Insulin action in the central nervous system is a major regulator of energy balance and
cognitive processes. The development of central insulin resistance is associated with …
cognitive processes. The development of central insulin resistance is associated with …
Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation …
Atypical antipsychotics (AAPs) have the tendency of inducing severe metabolic alterations
like obesity, diabetes mellitus, insulin resistance, dyslipidemia and cardiovascular …
like obesity, diabetes mellitus, insulin resistance, dyslipidemia and cardiovascular …
Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia
Dopamine (DA) D2-like receptors in both the central nervous system (CNS) and the
periphery are key modulators of metabolism. Moreover, disruption of D2-like receptor …
periphery are key modulators of metabolism. Moreover, disruption of D2-like receptor …
The effects of acute olanzapine exposure on central leptin mediated regulation of energy homeostasis and food intake
R Asgariroozbehani - 2022 - search.proquest.com
Second-generation antipsychotic (SGAs) use is associated with severe metabolic side-
effects which may be due to disrupted actions of leptin in the brain. We investigated the …
effects which may be due to disrupted actions of leptin in the brain. We investigated the …