Pediatric renal tumor epidemiology: Global perspectives, progress, and challenges

J Libes, J Hol, JCA Neto, KL Vallance… - Pediatric blood & …, 2023 - Wiley Online Library
Pediatric renal tumors account for 3%–11% of childhood cancers, the most common of
which is Wilms tumor or nephroblastoma. Epidemiology plays a key role in cancer …

Characteristics and outcome of children with renal cell carcinoma: a narrative review

JN van der Beek, JI Geller, RR de Krijger, N Graf… - Cancers, 2020 - mdpi.com
Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly
occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC …

The classification of pediatric and young adult renal cell carcinomas registered on the children's oncology group (COG) protocol AREN03B2 after focused genetic …

MM Cajaiba, LM Dyer, JI Geller, LJ Jennings… - Cancer, 2018 - Wiley Online Library
BACKGROUND Renal cell carcinomas (RCCs) are rare in young patients. Knowledge of
their pathologic and molecular spectrum remains limited, and no prospective studies have …

MiTF/TFE translocation renal cell carcinomas: from clinical entities to molecular insights

A Simonaggio, D Ambrosetti, V Verkarre… - International Journal of …, 2022 - mdpi.com
MiTF/TFE translocation renal cell carcinoma (tRCC) is a rare and aggressive subtype of
RCC representing the most prevalent RCC in the pediatric population (up to 40%) and …

Characteristics and outcome of pediatric renal cell carcinoma patients registered in the International Society of Pediatric Oncology (SIOP) 93‐01, 2001 and UK …

JN van der Beek, JA Hol… - … Journal of Cancer, 2021 - Wiley Online Library
In children, renal cell carcinoma (RCC) is rare. This study is the first report of pediatric
patients with RCC registered by the International Society of Pediatric Oncology‐Renal …

Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors

AL Walz, M Maschietto, B Crompton… - Pediatric Blood & …, 2023 - Wiley Online Library
The expansion of knowledge regarding driver mutations for Wilms tumor (WT) and malignant
rhabdoid tumor of the kidney (MRT) and various translocations for other pediatric renal …

Characteristics and outcome of children with renal tumors in the Netherlands: The first five-year's experience of national centralization

P Roy, SE van Peer, MM de Witte, GAM Tytgat… - PLoS …, 2022 - journals.plos.org
Around 6% of all childhood malignancies represent renal tumors, of which a majority
includes Wilms tumor (WT). Although survival rates have improved over the last decades …

Renal Tumors of Childhood: Radiologic-Pathologic Correlation Part 2. The 2nd Decade: From the Radiologic Pathology Archives

EM Chung, GE Lattin Jr, KE Fagen, AM Kim… - Radiographics, 2017 - pubs.rsna.org
Malignant renal tumors account for 7% of childhood cancers, and Wilms tumors are by far
the most common—but not in older children and adolescents. Among individuals in the latter …

Renal tumors of childhood—a histopathologic pattern-based diagnostic approach

AHAG Ooms, GM Vujanić, E D'hooghe, P Collini… - Cancers, 2020 - mdpi.com
Renal tumors comprise approximately 7% of all malignant pediatric tumors. This is a highly
heterogeneous group of tumors, each with its own therapeutic management, outcome, and …

A study of axitinib, a VEGF receptor tyrosine kinase inhibitor, in children and adolescents with recurrent or refractory solid tumors: A Children's Oncology Group phase …

JI Geller, E Fox, BK Turpin, SL Goldstein, X Liu… - Cancer, 2018 - Wiley Online Library
Background Axitinib is an oral small molecule that inhibits receptor tyrosine kinases vascular
endothelial growth factor receptors 1 to 3. A phase 1 and pharmacokinetic (PK) trial …