Abstract Treatment of ocular diseases presents unique challenges and opportunities for the
clinician and for the clinical pharmacologist. Ophthalmic pharmaceuticals, typically given as …

Presbyopia is a common age-related visual impairment. With the aging of the population, the
incidence of presbyopia is increasing globally, becoming a worldwide public health concern …

Objective Preclinical models of seizures and epilepsy in rodents contributed substantially to
the discovery of currently available antiseizure medications. These were also broadly used …

Purpose To evaluate the efficacy of 0.2% and 0.4% pilocarpine HCl (CSF-1) for the
treatment of presbyopia and to determine the contributions of pilocarpine HCl and diclofenac …

Purpose: The purpose of this study was to explore risk factors for symptomatic presbyopia,
defined as near add power≥ 1.50 diopters, in patients with glaucoma. Methods: Treated …

Background To study the ultra-trace simultaneous determination of drugs, the colorimetric
method in combination with chemometrics can be used. Objective In this study, a simple …

Introduction The phase 3, randomized, vehicle-controlled, 14-day VIRGO study evaluated
the efficacy and safety of twice-daily dosing of pilocarpine hydrochloride ophthalmic solution …

Presbyopia, a prevalent age-related condition impairing near vision, affects over a billion
people globally. While conventional treatments like corrective lenses and surgery exist, they …

Abstract Presbyopia affects between 1.7 and 2 billion people worldwide. Presbyopia
significantly impacts productivity and quality of life in both developed and developing …

La presbicia afecta a entre 1.700 y 2.000 millones de personas en todo el mundo. La
presbicia impacta significativamente la productividad y la calidad de vida tanto en países …