Food which is consumed by living organisms contains many antioxidants often with different
antioxidant abilities. In the case of antioxidants mixture its potential is not always an additive …

This paper is the thirty-ninth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2016 …

Natural products (NPs), including traditional Chinese medicine (TCM), have been long and
widely used in the prevention and treatment of central nervous system (CNS) diseases by …

Abstract Syzygium aromaticum (L.) Merr. & LM Perry (Mirtaceae) and Rosmarinus officinalis
L.(Lamiaceae) are both medicinal plants used for centuries to alleviate pain. The aim of the …

The Annonaceae is one of the plant families with members that are credited with numerous
pharmacological functions. Among the group of compounds responsible for these …

This study investigated the antiinflammatory properties of betulinic acid (BA) and xylopic
acid (XA) extracted from Margaritaria discoidea and Xylopia aethiopica, respectively. M …

Introduction. Depression affects an estimated 350 million people worldwide and is
implicated in up to 60% of suicides. Only about 60–70% of patients respond to …

Xylopic acid (XA) is a bioactive diterpene kaurene isolate of the Guinea pepper fruit, Xylopia
aethiopica (Annonaceae) with numerous well-established biological effects. In this study, we …

Stability studies of active pharmaceutical ingredients (APIs) remain an essential quality
requirement of the pharmaceutical industry. Stability data of an API could guide in the choice …

Introduction: The local peripheral combination of analgesic drugs with herbal derivatives
may have beneficial effects. Information on the action mechanism of these interactions …