Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …
showed a variety of pharmacological properties, and its derivatives propose a high degree …
Recent developments in biological activities of chalcones: A mini review
Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …
including synthetic and natural products. Synthetic manipulations of chalcones or their …
Chalcone: a promising bioactive scaffold in medicinal chemistry
Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review
Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
Chalcone scaffolds as anti-infective agents: Structural and molecular target perspectives
In recent years, widespread outbreak of numerous infectious diseases across the globe has
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …
Molecular modeling studies on 2, 4-disubstituted imidazopyridines as anti-malarials: Atom-based 3D-QSAR, molecular docking, virtual screening, in-silico ADMET and …
SN Mali, A Pandey - Journal of Computational Biophysics and …, 2021 - World Scientific
Malarial parasites have been reported for moderate-high resistance towards classical
antimalarial agents and henceforth development of newer novel chemical entities targeting …
antimalarial agents and henceforth development of newer novel chemical entities targeting …
Synthesis, characterization, molecular docking and in vitro antimalarial properties of new carboxamides bearing sulphonamide
Sulphonamides and carboxamides have shown large number of pharmacological properties
against different types of diseases among which is malaria. Twenty four new carboxamide …
against different types of diseases among which is malaria. Twenty four new carboxamide …
Methyl Chavicol and Its Synthetic Analogue as Possible Antioxidant and Antilipase Agents Based on the In Vitro and In Silico Assays
BCS Santos, AS Pires, CH Yamamoto… - Oxidative medicine …, 2018 - Wiley Online Library
This study investigated the in vitro and in silico biological properties of the methyl chavicol
(MC) and its analogue 2‐[(4‐methoxyphenyl) methyl] oxirane (MPMO), emphasizing the …
(MC) and its analogue 2‐[(4‐methoxyphenyl) methyl] oxirane (MPMO), emphasizing the …
Solidagenone from Solidago chilensis Meyen inhibits skin inflammation in experimental models
SS Valverde, BCS Santos… - Basic & Clinical …, 2021 - Wiley Online Library
Solidagenone (SOL) is a labdane‐type diterpenoid found in Solidago chilensis, a plant
traditionally used to treat skin diseases, kidney pain and ovarian inflammation. In this study …
traditionally used to treat skin diseases, kidney pain and ovarian inflammation. In this study …
Pro-Gly based dipeptide containing sulphonamide functionality, their antidiabetic, antioxidant, and anti-inflammatory activities. Synthesis, characterization and …
The increasing resistance to antidiabetic, antioxidant, and anti-inflammatory drugs are
complex and severe health issues these days, as many drugs available on the market are …
complex and severe health issues these days, as many drugs available on the market are …