Pharmacologic neuroprotection for functional outcomes after traumatic brain injury: a systematic review of the clinical literature
Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
The deleterious effects of secondary brain injury may be attenuated by early …
The deleterious effects of secondary brain injury may be attenuated by early …
Prevalence of alcohol and other drug use in patients presenting to hospital for fall-related injuries: a systematic review
Background Alcohol and other drug (AOD) use is a key preventable risk factor for serious
injuries. Prevention strategies to date have largely focused on transport injuries, despite …
injuries. Prevention strategies to date have largely focused on transport injuries, despite …
Alcohol and drug use before and during the first year after traumatic brain injury
S Beaulieu-Bonneau, F St-Onge… - The Journal of head …, 2018 - journals.lww.com
Objectives: To compare individuals with mild and moderate/severe traumatic brain injury
(TBI) on alcohol and drug use and substance use disorders before and in the first year post …
(TBI) on alcohol and drug use and substance use disorders before and in the first year post …
Effects of positive blood alcohol concentration on outcome and systemic interleukin-6 in major trauma patients
B Relja, J Menke, N Wagner, B Auner, M Voth, C Nau… - Injury, 2016 - Elsevier
Background The influence of alcohol on the outcome after major trauma remains
controversial. In several recent studies, alcohol has been associated with neuroprotective …
controversial. In several recent studies, alcohol has been associated with neuroprotective …
Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury
A Chandrasekar, F olde Heuvel, A Palmer… - International …, 2017 - Elsevier
Ethanol intoxication is a common comorbidity in traumatic brain injury. To date, the effect of
ethanol on TBI pathogenic cascades and resulting outcomes remains debated. A closed …
ethanol on TBI pathogenic cascades and resulting outcomes remains debated. A closed …
[HTML][HTML] Ethanol decreases inflammatory response in human lung epithelial cells by inhibiting the canonical NF-kB-pathway
K Mörs, JA Hörauf, S Kany, N Wagner… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Alcohol (ethanol, EtOH) as significant contributor to traumatic injury is
linked to suppressed inflammatory response, thereby influencing clinical outcomes. Alcohol …
linked to suppressed inflammatory response, thereby influencing clinical outcomes. Alcohol …
Alcohol intoxication reduces systemic interleukin-6 levels and leukocyte counts after severe TBI compared with not intoxicated TBI patients
N Wagner, A Akbarpour, K Mörs, M Voth, P Störmann… - Shock, 2016 - journals.lww.com
Background: The effect of alcohol consumption on inflammatory state and outcome in brain-
injured patients remains controversial. We analyzed the influence of positive blood alcohol …
injured patients remains controversial. We analyzed the influence of positive blood alcohol …
Circulating extracellular vesicles and their miR “Barcode” differentiate alcohol drinkers with liver injury and those without liver injury in severe trauma patients
A Eguchi, N Franz, Y Kobayashi, M Iwasa… - Frontiers in …, 2019 - frontiersin.org
Short Summary: Extracellular vesicles (EVs), released during tissue/cell injury, contain a
“barcode” indicating specific microRNAs (miRs) that can uncover their origin. We examined …
“barcode” indicating specific microRNAs (miRs) that can uncover their origin. We examined …
Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responses
A Chandrasekar, B Aksan, F olde Heuvel… - Experimental …, 2018 - Elsevier
Ethanol intoxication is a risk factor for traumatic brain injury (TBI) but clinical evidence
suggests that it may actually improve the prognosis of intoxicated TBI patients. We have …
suggests that it may actually improve the prognosis of intoxicated TBI patients. We have …
Factors with the strongest prognostic value associated with in-hospital mortality rate among patients operated for acute subdural and epidural hematoma
B Kulesza, M Mazurek, A Nogalski, R Rola - European Journal of Trauma …, 2021 - Springer
Introduction Traumatic brain injury (TBI) still remains a serious health problem and is called
a “silent epidemic”. Each year in Europe 262 per 100,000 individuals suffer from TBI. The …
a “silent epidemic”. Each year in Europe 262 per 100,000 individuals suffer from TBI. The …