Development and challenges of antimicrobial peptide delivery strategies in bacterial therapy: A review

L Yao, Q Liu, Z Lei, T Sun - International Journal of Biological …, 2023 - Elsevier
The escalating global prevalence of antimicrobial resistance poses a critical threat,
prompting concerns about its impact on public health. This predicament is exacerbated by …

Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation

G Nabil, K Bhise, S Sau, M Atef, HA El-Banna… - Drug Discovery …, 2019 - Elsevier
Cancer is the second highest cause of death worldwide. Several therapeutic approaches,
such as conventional chemotherapy, antibodies and small molecule inhibitors and …

Hybrid PEGylated chitosan/PLGA nanoparticles designed as pH-responsive vehicles to promote intracellular drug delivery and cancer chemotherapy

SJ Huang, TH Wang, YH Chou, HMD Wang… - International Journal of …, 2022 - Elsevier
To achieve effective intracellular anticancer drug release for boosted antitumor efficacy, the
acidity-responsive nanovehicles for doxorubicin (DOX) delivery were fabricated by tailor …

Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity

B Zhang, S Wan, X Peng, M Zhao, S Li, Y Pu… - Journal of materials …, 2020 - pubs.rsc.org
Doxorubicin (DOX) is a widely-used anticancer drug, but its cardiotoxicity severely hampers
its potency in chemotherapy. Herein, human serum albumin (HSA) is engaged as a …

Targeting drug delivery and efficient lysosomal escape for chemo-photodynamic cancer therapy by a peptide/DNA nanocomplex

Q Wang, Z He, H Zhu, W Gao, N Zhang, J Li… - Journal of Materials …, 2022 - pubs.rsc.org
A peptide/DNA nanocomplex was developed for the targeted delivery of chemotherapeutics
and photosensitizers to cancer cells for efficient combination therapy. The chemotherapeutic …

pH-controlled intracellular in situ reversible assembly of a photothermal agent for smart chemo-photothermal synergetic therapy and ATP imaging

J Zhang, YX Cui, XN Feng, M Cheng… - … applied materials & …, 2019 - ACS Publications
To advance anti-tumor efficiency and lessen the adverse effect caused by nanodrug
residues in the body, a smart nanoagent system is developed and successfully used in …

DNA polymer nanoparticles programmed via supersandwich hybridization for imaging and therapy of cancer cells

N Li, MH Xiang, JW Liu, H Tang, JH Jiang - Analytical chemistry, 2018 - ACS Publications
Spherical nucleic acid (SNA) constructs are promising new single entity materials, which
possess significant advantages in biological applications. Current SNA-based drug delivery …

Clay nanosheets simultaneously intercalated and stabilized by PEGylated chitosan as drug delivery vehicles for cancer chemotherapy

HJ Huang, SY Huang, TH Wang, TY Lin… - Carbohydrate …, 2023 - Elsevier
Montmorillonite (MMT) has been frequently utilized as drug vehicles due to its high specific
surface area, excellent cation exchange capacity and biocompatibility. However, the …

ATP/Hyals dually responsive core-shell hyaluronan/chitosan-based drug nanocarrier for potential application in breast cancer therapy

H Li, S Zhuang, Y Yang, F Zhou, J Rong… - International Journal of …, 2021 - Elsevier
The stability of self-assembled drug nanocarriers during blood circulation and the controlled
intracellular drug delivery are two challenges in cancer therapy. In this paper, we …

[HTML][HTML] Bioresponsive Polymers for Nanomedicine—Expectations and Reality!

S Quader, JFR Van Guyse - Polymers, 2022 - mdpi.com
Bioresponsive polymers in nanomedicine have been widely perceived to selectively activate
the therapeutic function of nanomedicine at diseased or pathological sites, while sparing …