Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …

Objective To systematically review the literature on the relationship between markers of
inflammation and pain in patients with knee osteoarthritis (OA). Methods We searched …

The success of disease-modifying osteoarthritis drug (DMOAD) development is still elusive.
While there have been successes in preclinical and early clinical studies, phase 3 clinical …

Osteoarthritis (OA) is the most common form of joint disease and a major cause of pain and
disability in the adult population. Interestingly, there are patients with symptomatic OA …

Osteoarthritis (OA), the most common rheumatic disease, is characterized by joint-space
narrowing due to progressive cartilage degradation and alterations in subchondral bone …

Osteoarthritis is the most prevalent arthritis typically characterized by degradation of
cartilage. However, its pathogenesis is not fully understood. Currently, osteoarthritis is best …

OA is a complex disease involving mechanical, metabolic and inflammatory contributions to
its aetiology. A key risk factor, obesity, is becoming an increasing focus of research due to its …

The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …

Knee osteoarthritis (OA) is the most common joint disease. Body adipose tissue has been
shown to be related to the development and progression of knee OA. Among systemic …