Heat shock proteins (HSPs) constitute a large family of proteins involved in protein folding
and maturation whose expression is induced by heat shock or other stressors. The major …

The 70-kDa heat shock proteins (HSP70s) are abundantly present in cancer, providing
malignant cells selective advantage by suppressing multiple apoptotic pathways, regulating …

Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

Biochemical and genetic studies on cellular and animal models on the mechanism (s) of
action of phytochemicals provide a functional explanation of how and why a diet rich in fruits …

ETHNOPHARMACOLOGICAL RELEVANCE: Quercetin is a ubiquitous flavonoid that is
present in numerous plants that are utilized in many different cultures for their nervous …

The article features quercetin, one of the subclasses of flavonoid compounds. The dietary
presence of quercetin is provided in foods and in the form of quercetin glycosides. Factors …

Quercetin (QCT) is a flavonoid, abundantly present in plants and has gained considerable
interest for its antioxidant property and chemo preventive activity. Bioavailability of QCT is …

Food-derived flavonoid quercetin, widely distributed in onions, apples, and tea, is able to
inhibit growth of various cancer cells indicating that this compound can be considered as a …

Despite the advances in biomedical research and clinical applications, cancer remains a
leading cause of death worldwide. Given the limitations of conventional chemotherapeutics …

Pancreatic ductal adenocarcinoma (PDAC) is considered one of the deadliest human
cancers, with 1-5% 5-year survival rates (~ 6-month median survival duration) despite …