Background Neuroinflammatory processes have been hypothesized to play a role in the
pathogenesis of psychiatric and neurological diseases. Studies on this topic often rely on …

Pericytes are specialized cells located in close proximity to endothelial cells within the
microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls …

Amyotrophic lateral sclerosis (ALS) is a progressively fatal neurodegenerative disease
affecting motor neurons in the brain and spinal cord. In this study, we investigated gene …

The choroid plexus (ChP) is a vital brain barrier and source of cerebrospinal fluid (CSF).
Here, we use longitudinal two-photon imaging in awake mice and single-cell transcriptomics …

This review examines the crucial roles of the choroid plexus (ChP) in central nervous system
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly
understood clinical heterogeneity, underscored by significant differences in patient age at …

Objective Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease with a complex
etiology that lacks biomarkers predicting disease progression. The objective of this study …

Leukocyte migration into the central nervous system (CNS) represents a central process in
the development of neurological diseases with a detrimental inflammatory component …

The choroid plexus (CP), located in each of the four ventricles of the brain, is formed by a
monolayer of epithelial cells that surrounds a highly vascularized connective tissue with …

Brain vascular integrity is critical for brain health, and its disruption is implicated in many
brain pathologies, including psychiatric disorders. Brain-vascular barriers are a complex …