[HTML][HTML] Relationship between epithelial-to-mesenchymal transition and tumor-associated macrophages in colorectal liver metastases

A Gazzillo, MA Polidoro, C Soldani… - International Journal of …, 2022 - mdpi.com
The liver is the most common metastatic site in colorectal cancer (CRC) patients. Indeed, 25–
30% of the cases develop colorectal liver metastasis (CLM), showing an extremely poor 5 …

[HTML][HTML] A New Era of Integration between Multiomics and Spatio-Temporal Analysis for the Translation of EMT towards Clinical Applications in Cancer

A Fonseca Teixeira, S Wu, R Luwor, HJ Zhu - Cells, 2023 - mdpi.com
Epithelial-mesenchymal transition (EMT) is crucial to metastasis by increasing cancer cell
migration and invasion. At the cellular level, EMT-related morphological and functional …

[HTML][HTML] Homotypic entosis as a potential novel diagnostic marker in breast cancer

I Dziuba, AM Gawel, P Tyrna, J Machtyl… - International Journal of …, 2023 - mdpi.com
Homotypic entotic figures, which are a form of “cell-in-cell” structures, are considered a
potential novel independent prognostic marker in various cancers. Nevertheless, the …

PGC1α-mediated fatty acid oxidation promotes TGFβ1-induced epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma

J Quan, N Li, Y Tan, H Liu, W Liao, Y Cao, X Luo - Life Sciences, 2022 - Elsevier
Aim Cancer cells frequently undergo metabolic reprogramming, which contributes to
tumorigenicity and malignancy. Unlike primary cancers, during the process of invasion and …

[HTML][HTML] Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and …

F Guo, F Xu, S Li, Y Zhang, D Lv, L Zheng… - European Journal of …, 2024 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disease
characterized by irreversible scarring of the lung parenchyma. Despite various interventions …

[HTML][HTML] Reversing an oncogenic epithelial-to-mesenchymal transition program in breast cancer reveals actionable immune suppressive pathways

MM Williams, SA Hafeez, JL Christenson, KI O'Neill… - Pharmaceuticals, 2021 - mdpi.com
Approval of checkpoint inhibitors for treatment of metastatic triple negative breast cancer
(mTNBC) has opened the door for the use of immunotherapies against this disease …

[HTML][HTML] Pancreatic ductal adenocarcinoma cortical mechanics and clinical implications

S Angstadt, Q Zhu, EM Jaffee, DN Robinson… - Frontiers in …, 2022 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to low
therapeutic response rates and poor prognoses. Majority of patients present with symptoms …

[HTML][HTML] Identification and analysis of MSC-Exo-derived LncRNAs related to the regulation of EMT in hypospadias

M Chang, H Gao, Y Li, C Ding, Z Lu, D Li… - BMC Medical …, 2024 - Springer
Objective This study aims to screen the differentially expressed long non-coding RNAs
(DELncRNAs) related to the regulation of epithelial-mesenchymal transition (EMT) in …

Identification and analysis of epithelial‐mesenchymal transition‐related key long non‐coding RNAs in hypospadias

H Gao, C Ding, M Chang, Z Lu, D Li, D Bi… - IET Systems …, 2024 - Wiley Online Library
EMT dysfunction is a dominant mechanisms of hypospadias. Thus, identification of EMT‐
related lncRNAs based on transcriptome sequencing data of hypospadias might provide …

[PDF][PDF] A Novel Fatty Acid Metabolism Signature Predicts Prognoses, Tumor Immune Microenvironment, and Immunotherapy Response In Lung Adenocarcinoma

D Fu, B Zhang, W Fan, X Wang - 2023 - scholar.archive.org
Background: Lung adenocarcinoma (LUAD) is the most common and aggressive subtype of
non-small cell lung cancer. Aberrant fatty acid metabolism (FAM) has been demonstrated to …