Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19

RT Eastman, JS Roth, KR Brimacombe… - ACS central …, 2020 - ACS Publications
The global pandemic of SARS-CoV-2, the causative viral pathogen of COVID-19, has driven
the biomedical community to action—to uncover and develop antiviral interventions. One …

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS‐CoV, MERS‐CoV, and 2019‐nCoV

J Liu, X Zheng, Q Tong, W Li, B Wang… - Journal of medical …, 2020 - Wiley Online Library
Abstract First reported from Wuhan, The People's Republic of China, on 31 December 2019,
the ongoing outbreak of a novel coronavirus (2019‐nCoV) causes great global concerns …

[HTML][HTML] The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes

H Zhang, Z Kang, H Gong, D Xu, J Wang, Z Li, X Cui… - BioRxiv, 2020 - biorxiv.org
Since December 2019, a newly identified coronavirus (2019 novel coronavirus, 2019-nCov)
is causing outbreak of pneumonia in one of largest cities, Wuhan, in Hubei province of …

Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

H Zhang, Z Kang, H Gong, D Xu, J Wang, Z Li, Z Li… - Gut, 2020 - gut.bmj.com
Objective Since December 2019, a newly identified coronavirus (severe acute respiratory
syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan …

COVID-19 for the cardiologist: basic virology, epidemiology, cardiac manifestations, and potential therapeutic strategies

D Atri, HK Siddiqi, JP Lang, V Nauffal… - Basic to Translational …, 2020 - jacc.org
Summary Coronavirus disease-2019 (COVID-19), a contagious disease caused by severe
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has reached pandemic status. As …

Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19

I Bernard, D Limonta, LK Mahal, TC Hobman - Viruses, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

A cohort autopsy study defines COVID-19 systemic pathogenesis

XH Yao, T Luo, Y Shi, ZC He, R Tang, PP Zhang, J Cai… - Cell research, 2021 - nature.com
Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by
dysfunction of the lungs and extrapulmonary organs. However, the organotropism of SARS …

The first, holistic immunological model of COVID‐19: implications for prevention, diagnosis, and public health measures

PM Matricardi, RW Dal Negro… - Pediatric Allergy and …, 2020 - Wiley Online Library
The natural history of COVID‐19 caused by SARS‐CoV‐2 is extremely variable, ranging
from asymptomatic or mild infection, mainly in children, to multi‐organ failure, eventually …

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes

D Bojkova, JUG Wagner, M Shumliakivska… - Cardiovascular …, 2020 - academic.oup.com
Aims Coronavirus disease 2019 is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and has emerged as a global pandemic. SARS-CoV-2 …