Fluorinated nucleosides are an important class of modified nucleosides that have
demonstrated therapeutic potential for treating various human diseases, especially viral …

Infrared multiple photon dissociation (IRMPD) spectroscopy is a powerful tool used to probe
the vibrational modes–and, by extension, the structure—of an ion within an ion trap mass …

Dissociations of DNA trinucleotide codons as gas-phase singly and doubly protonated ions
were studied by tandem mass spectrometry using 15N-labeling to resolve identity in the …

Fluorinated nucleosides are well-established as anticancer and antiviral medications. As
with many pharmaceuticals, the effects of fluorine modifications are often only partially …

Employing the microhydration model that involves two to five explicit water molecules, two
plausible dissociative hydrolysis pathways of 2′, 3′-didehydro-2′, 3′-dideoxyuridine …

Fluoro‐substitution on the ribose moiety (eg, 2'‐F‐deoxyribonucleotide) represents a
popular way to modulate the ribose conformation and, hence, the structure and function of …

Nucleosides are the building blocks of the genetic materials of life, DNA and RNA.
Modifications to the canonical nucleoside forms, both natural and synthetic, have substantial …

Compound identification, characterization and quantification has been the key elements
behind development of analytical chemistry as a field. Mass spectrometry (MS) is one of the …

Gas-phase conformations of the deprotonated disodium cationized 2′-deoxycytidine-5′-
monophosphate and cytidine-5′-monophosphate nucleotides,[pdCyd− H+ 2Na]+ and …