The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration

TH Hutson, S Di Giovanni - Nature Reviews Neurology, 2019 - nature.com
Over the past decade, we have witnessed a flourishing of novel strategies to enhance
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …

[HTML][HTML] Review on motor imagery based BCI systems for upper limb post-stroke neurorehabilitation: From designing to application

MA Khan, R Das, HK Iversen… - Computers in biology and …, 2020 - Elsevier
Strokes are a growing cause of mortality and many stroke survivors suffer from motor
impairment as well as other types of disabilities in their daily life activities. To treat these …

[HTML][HTML] Robotic rehabilitation and spinal cord injury: a narrative review

M Mekki, AD Delgado, A Fry, D Putrino, V Huang - Neurotherapeutics, 2018 - Elsevier
Mobility after spinal cord injury (SCI) is among the top goals of recovery and improvement in
quality of life. Those with tetraplegia rank hand function as the most important area of …

[HTML][HTML] And yet it moves: recovery of volitional control after spinal cord injury

G Taccola, D Sayenko, P Gad, Y Gerasimenko… - Progress in …, 2018 - Elsevier
Preclinical and clinical neurophysiological and neurorehabilitation research has generated
rather surprising levels of recovery of volitional sensory-motor function in persons with …

Neuromodulation in the restoration of function after spinal cord injury

ND James, SB McMahon, EC Field-Fote… - The Lancet …, 2018 - thelancet.com
Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been
successful as a treatment approach in several neurological disorders, including deep brain …

Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease

AK Vose, JF Welch, J Nair, EA Dale, EJ Fox… - Experimental …, 2022 - Elsevier
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …

Corticospinal-motor neuronal plasticity promotes exercise-mediated recovery in humans with spinal cord injury

HJ Jo, MA Perez - Brain, 2020 - academic.oup.com
Rehabilitative exercise in humans with spinal cord injury aims to engage residual neural
networks to improve functional recovery. We hypothesized that exercise combined with non …

Cortical and subcortical effects of transcutaneous spinal cord stimulation in humans with tetraplegia

FD Benavides, HJ Jo, H Lundell… - Journal of …, 2020 - Soc Neuroscience
An increasing number of studies supports the view that transcutaneous electrical stimulation
of the spinal cord (TESS) promotes functional recovery in humans with spinal cord injury …

Targeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury

JG McPherson, RR Miller… - Proceedings of the …, 2015 - National Acad Sciences
Use-dependent movement therapies can lead to partial recovery of motor function after
neurological injury. We attempted to improve recovery by developing a neuroprosthetic …

Reticulospinal contributions to gross hand function after human spinal cord injury

SN Baker, MA Perez - Journal of Neuroscience, 2017 - Soc Neuroscience
Multiple descending motor pathways likely contribute to the recovery of hand motor function
following spinal cord injury (SCI). Reticulospinal neurons project to spinal motor neurons …