Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications

AK Agrahari, P Bose, MK Jaiswal, S Rajkhowa… - Chemical …, 2021 - ACS Publications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Cu-catalyzed click reaction in carbohydrate chemistry

VK Tiwari, BB Mishra, KB Mishra, N Mishra… - Chemical …, 2016 - ACS Publications
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Comprehensive review on the anti-bacterial activity of 1, 2, 3-triazole hybrids

B Zhang - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

Click chemistry: 1, 2, 3‐triazoles as pharmacophores

SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …

Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold

B Findlay, GG Zhanel, F Schweizer - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Naturally occurring cationic antimicrobial peptides (AMPs) and their mimics form a diverse
class of antibacterial agents currently validated in preclinical and clinical settings for the …

Design and application of antimicrobial peptide conjugates

A Reinhardt, I Neundorf - International journal of molecular sciences, 2016 - mdpi.com
Antimicrobial peptides (AMPs) are an interesting class of antibiotics characterized by their
unique antibiotic activity and lower propensity for developing resistance compared to …

Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside …

MP Mingeot-Leclercq, JL Décout - MedChemComm, 2016 - pubs.rsc.org
Hereunder, we highlight bacterial membrane anionic lipids as attractive targets in the design
of antibacterial drugs which can be effective against both Gram-positive and Gram-negative …

Aminoglycoside‐based biomaterials: from material design to antibacterial and gene delivery applications

J Hu, L Yang, X Cheng, Y Li… - Advanced Functional …, 2021 - Wiley Online Library
Aminoglycosides are a family of naturally isolated or chemically semi‐synthesized
antibiotics consisting of aminocyclitols with several amino and saccharide units. The unique …

Cationic surfactants derived from lysine: effects of their structure and charge type on antimicrobial and hemolytic activities

A Colomer, A Pinazo, MA Manresa… - Journal of Medicinal …, 2011 - ACS Publications
Three different sets of cationic surfactants from lysine have been synthesized. The first group
consists of three monocatenary surfactants with one lysine as the cationic polar head with …

Design, synthesis, and evaluation of novel fluoroquinolone− aminoglycoside hybrid antibiotics

V Pokrovskaya, V Belakhov… - Journal of medicinal …, 2009 - ACS Publications
A series of new hybrid structures containing fluoroquinolone (ciprofloxacin) and
aminoglycoside (neomycin) antibiotics linked via 1, 2, 3-triazole moiety were designed and …