Endometriosis: Recent advances that could accelerate diagnosis and improve care
Endometriosis is a common disorder associated with pain, gastrointestinal and urinary
symptoms, infertility, and fatigue. It is defined by the presence of endometrial-like lesions …
symptoms, infertility, and fatigue. It is defined by the presence of endometrial-like lesions …
[HTML][HTML] Pathogenesis of Endometriosis and Endometriosis-Associated Cancers
A Adilbayeva, J Kunz - International journal of molecular sciences, 2024 - mdpi.com
Endometriosis is a hormone-dependent, chronic inflammatory condition that affects 5–10%
of reproductive-aged women. It is a complex disorder characterized by the growth of …
of reproductive-aged women. It is a complex disorder characterized by the growth of …
The Known, the Unknown and the Future of the Pathophysiology of Endometriosis
MA Ochoa Bernal, AT Fazleabas - International Journal of Molecular …, 2024 - mdpi.com
Endometriosis is one of the most common causes of chronic pelvic pain and infertility,
affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between …
affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between …
Long-Term Maintenance of Viable Human Endometrial Epithelial Cells to Analyze Estrogen and Progestin Effects
MA Riaz, FL Kary, A Jensen, F Zeppernick… - Cells, 2024 - mdpi.com
There are fewer investigations conducted on human primary endometrial epithelial cells
(HPEECs) compared to human primary endometrial stromal cells (HPESCs). One of the …
(HPEECs) compared to human primary endometrial stromal cells (HPESCs). One of the …
[HTML][HTML] Single-cell transcriptomic analysis of immune cell dynamics in the healthy human endometrium
The microenvironment of the endometrial immune system is crucial to the success of
placental implantation and healthy pregnancy. However, the functionalities of immune cells …
placental implantation and healthy pregnancy. However, the functionalities of immune cells …
Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions
The mechanisms underlying the pathophysiology of endometriosis, characterized by the
presence of endometrium-like tissue outside the uterus, remain poorly understood. This …
presence of endometrium-like tissue outside the uterus, remain poorly understood. This …
Tracing Endometriosis: Coupling deeply phenotyped, single-cell based Endometrial Differences and AI for disease pathology and prediction
L Duempelmann, S Sheppard, A Duo, J Skrabalova… - bioRxiv, 2024 - biorxiv.org
Endometriosis, affecting 1 in 9 women, presents treatment and diagnostic challenges. To
address these issues, we generated the biggest single-cell atlas of endometrial tissue to …
address these issues, we generated the biggest single-cell atlas of endometrial tissue to …
Single-Cell and Spatial Transcriptomic Profiling Revealed Niche Interactions Sustaining Growth of Endometriotic Lesions
S Liu, X Li, Z Gu, J Wu, S Jia, J Shi, Y Dai, Y Wu… - Available at SSRN … - papers.ssrn.com
Endometriosis is a chronic condition with limited therapeutic options. The molecular
aberrations promoting ectopic attachment and interactions with the local microenvironment …
aberrations promoting ectopic attachment and interactions with the local microenvironment …