Adrenal insufficiency

ES Husebye, SH Pearce, NP Krone, O Kämpe - The Lancet, 2021 - thelancet.com
Adrenal insufficiency can arise from a primary adrenal disorder, secondary to
adrenocorticotropic hormone deficiency, or by suppression of adrenocorticotropic hormone …

Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline

SR Bornstein, B Allolio, W Arlt, A Barthel… - The Journal of …, 2016 - academic.oup.com
Objective: This clinical practice guideline addresses the diagnosis and treatment of primary
adrenal insufficiency. Participants: The Task Force included a chair, selected by The Clinical …

Endocrinology in the time of COVID-19: Management of adrenal insufficiency

W Arlt, SE Baldeweg, SHS Pearce… - European Journal of …, 2020 - academic.oup.com
We provide guidance on prevention of adrenal crisis during the global COVID-19 crisis, a
time with frequently restricted access to the usual level of healthcare. Patients with adrenal …

Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency …

AM Isidori, MA Venneri, C Graziadio… - The lancet Diabetes & …, 2018 - thelancet.com
Background Conventional treatment of patients with adrenal insufficiency involves
administration of glucocorticoids multiple times a day and has been associated with weight …

Epidemiology, pathogenesis, and diagnosis of Addison's disease in adults

C Betterle, F Presotto, J Furmaniak - Journal of endocrinological …, 2019 - Springer
Background Addison's disease (AD) is a rare disorder and among adult population in
developed countries is most commonly caused by autoimmunity. In contrast, in children …

Expanding the phenotypic and genotypic landscape of autoimmune polyendocrine syndrome type 1

EM Orlova, LS Sozaeva, MA Kareva… - The Journal of …, 2017 - academic.oup.com
Context Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare monogenic
autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene and …

Clinical and immunological characteristics of autoimmune Addison disease: a nationwide Swedish multicenter study

F Dalin, G Nordling Eriksson, P Dahlqvist… - The Journal of …, 2017 - academic.oup.com
Context: Studies of the clinical and immunological features of autoimmune Addison disease
(AAD) are needed to understand the disease burden and increased mortality. Objective: To …

Group 1. Epidemiology of primary and secondary adrenal insufficiency: prevalence and incidence, acute adrenal insufficiency, long-term morbidity and mortality

O Chabre, B Goichot, D Zenaty, J Bertherat - Annales d'endocrinologie, 2017 - Elsevier
The prevalence of primary adrenal insufficiency is estimated at between 82–144/million, with
auto-immunity being the most common cause in adults and genetic causes, especially …

Primary adrenal insufficiency in childhood: data from a large nationwide cohort

D Capalbo, C Moracas, M Cappa… - The Journal of …, 2021 - academic.oup.com
Context Primary adrenal insufficiency (PAI) is a rare and potentially life-threatening condition
that is poorly characterized in children. Objective To describe causes, presentation …

Autoimmune Addison's disease

S Saverino, A Falorni - Best Practice & Research Clinical Endocrinology & …, 2020 - Elsevier
Primary adrenal insufficiency (PAI) occurs in 1/5000–1/7000 individuals in the general
population. Autoimmune Addison's disease (AAD) is the major cause of PAI and is a major …