Current cancer immunotherapies are primarily predicated on αβ T cells, with a stringent
dependence on MHC-mediated presentation of tumour-enriched peptides or unique …

Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

The potential of cancer immunotherapy relies on the mobilization of immune cells capable of
producing antitumour cytokines and effectively killing tumour cells. These are major …

Abstract γδ T cells have several innate cell-like features that allow their early activation
following recognition of conserved stress-induced ligands. Here we review recent …

Gamma delta T (γδ T) cells are among the most potent cytotoxic lymphocytes. Activating anti–
butyrophilin 3A (BTN3A) antibodies prime diverse tumor cell types to be killed by Vγ9Vδ2 T …

A growing number of studies have shown that γδ T cells play a pivotal role in mediating the
clearance of tumors and pathogen-infected cells with their potent cytotoxic, cytolytic, and …

The investigation of γδ T cells has identified a rapid lymphoid stress-surveillance response
to microbial and nonmicrobial tissue perturbation. In addition to providing local protection …

The presence of fucose on IgG1 Asn-297 N-linked glycan is the modification of the human
IgG1 Fc structure with the most significant impact on FcɣRIII affinity. It also significantly …

Increasing immunological knowledge and advances in techniques lay the ground for more
efficient and broader application of immunotherapies. gamma delta (γδ) T-cells possess …