Proteins and enzymes in the cell nucleus require physical access to their DNA target sites in
order to perform genomic tasks such as gene activation and transcription. Hence, chromatin …

Motivation Efficient tapping into genomic information from a single microscopic image of an
intact DNA molecule is an outstanding challenge and its solution will open new frontiers in …

Carcinogenesis often involves significant alterations in the cancer genome, marked by large
structural variants (SVs) and copy number variations (CNVs) that are difficult to capture with …

Motivation Genomics-based diagnostic methods that are quick, precise, and economical are
essential for the advancement of precision medicine, with applications spanning the …