Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

X Chen, C Shi, M He, S Xiong, X Xia - Signal transduction and targeted …, 2023 - nature.com
The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective

JPO Li, H Liu, DSJ Ting, S Jeon, RVP Chan… - Progress in retinal and …, 2021 - Elsevier
The simultaneous maturation of multiple digital and telecommunications technologies in
2020 has created an unprecedented opportunity for ophthalmology to adapt to new models …

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

R Bourne, JD Steinmetz, S Flaxman… - The Lancet global …, 2021 - thelancet.com
Background To contribute to the WHO initiative, VISION 2020: The Right to Sight, an
assessment of global vision impairment in 2020 and temporal change is needed. We aimed …

Cataract and systemic disease: A review

MJ Ang, NA Afshari - Clinical & experimental ophthalmology, 2021 - Wiley Online Library
We review the current literature regarding the risk factors for cataract and the association
between cataract and systemic disease. Numerous epidemiologic studies have found that …

[HTML][HTML] The effect of lutein on eye and extra-eye health

S Buscemi, D Corleo, F Di Pace, ML Petroni, A Satriano… - Nutrients, 2018 - mdpi.com
Lutein is a carotenoid with reported anti-inflammatory properties. A large body of evidence
shows that lutein has several beneficial effects, especially on eye health. In particular, lutein …

Blue light exposure: ocular hazards and prevention—a narrative review

A Cougnard-Gregoire, BMJ Merle, T Aslam… - Ophthalmology and …, 2023 - Springer
Introduction Exposure to blue light has seriously increased in our environment since the
arrival of light emitting diodes (LEDs) and, in recent years, the proliferation of digital devices …

[HTML][HTML] Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways

Y Mi, C Wei, L Sun, H Liu, J Zhang, J Luo, X Yu… - Biomedicine & …, 2023 - Elsevier
Background Cataracts are the main cause of reversible blindness worldwide. The ageing of
the lens caused by ultraviolet B (UVB) radiation is mostly related to oxidative stress (OS) …

Refractive surgery beyond 2020

M Ang, D Gatinel, DZ Reinstein, E Mertens… - Eye, 2021 - nature.com
Refractive surgery refers to any procedure that corrects or minimizes refractive errors. Today,
refractive surgery has evolved beyond the traditional laser refractive surgery, embodied by …

Vitamin D and ocular diseases: a systematic review

HN Chan, XJ Zhang, XT Ling, CHT Bui… - International journal of …, 2022 - mdpi.com
The contributory roles of vitamin D in ocular and visual health have long been discussed,
with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper …

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …